Trends in gabapentin and baclofen exposures reported to U.S. poison centers - Reynolds K, Kaufman R, Korenoski A, Fennimore L, Shulman J, Lynch M.

Context: Prescriptions for nonopioid pharmacological therapies such as gabapentin and baclofen have been increasing. While gabapentin and baclofen are less likely than opioids to result in fatal overdose, they are each associated with dependence, mi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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Alcohol poisoning is a serious medical emergency due to the overconsumption of alcohol that can result in death. Overconsumption of alcohol affects many systems in the body. The liver, which works to eliminate toxins from the body, is not able to keep up with the high amount being ingested. In turn, the central nervous system becomes so depressed to the point that it cannot perform its normal, essential functions such as beating the heart and breathing. There are many factors that can determine whether or not an individual could suffer from alcohol poisoning, such as: Rate of alcohol consumption Tolerance and dependency ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism Detox Resources for Alcohol and Drugs/Opiates alcohol abuse alcohol detox alcohol treatment alcohol treatment center alcohol treatment facility Source Type: blogs
Conclusion: Comparisons of postmortem concentrations of specific drugs indicated that patients treated with methadone, buprenorphine, and implant naltrexone had comparable susceptibilities to lethal co-intoxication and that similar drug mixtures contributed to death. PMID: 31860367 [PubMed - as supplied by publisher]
Source: The American Journal of Drug and Alcohol Abuse - Category: Addiction Authors: Tags: Am J Drug Alcohol Abuse Source Type: research
BACKGROUND: There is an acute public health crisis from opioid-related poisoning and overdose in Canada. The Moss Park Overdose Prevention Site (MP-OPS) - an unsanctioned overdose prevention site - opened in a downtown park in Toronto in August 2017, when ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Background: Therapeutic use, overdose and recreational abuse of bupropion are increasing. The purpose of this study was to describe the incidence and outcomes of bupropion exposures reported to the Ontario Poison Centre in Canada, and to identify pr...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
OBJECTIVE: To examine the clinical outcomes of intentional overdoses involving triptans and ergotamines with a retrospective review of the National Poison Data System (NPDS). METHODS: This was a 5-year retrospective cross-sectional study (2014-2018...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Publication date: February 2020Source: Spatial and Spatio-temporal Epidemiology, Volume 32Author(s): Yusuf Ransome, S.V. Subramanian, Dustin T. Duncan, Daivid Vlahov, Joshua WarrenAbstractDrug- and alcohol-poisoning deaths remain current public health problems. Studies to date have typically focused on individual-level predictors of drug overdose deaths, and there remains a limited understanding of the spatiotemporal patterns and predictors of the joint outcomes. We use a hierarchical Bayesian spatiotemporal multivariate Poisson regression model on data from (N = 167) ZIP-codes between 2009 and 2014 in New York City to...
Source: Spatial and Spatio-temporal Epidemiology - Category: Epidemiology Source Type: research
Publication date: Available online 11 November 2019Source: Spatial and Spatio-temporal EpidemiologyAuthor(s): Yusuf Ransome, S.V. Subramanian, Dustin T. Duncan, Daivid Vlahov, Joshua WarrenAbstractDrug- and alcohol-poisoning deaths remain current public health problems. Studies to date have typically focused on individual-level predictors of drug overdose deaths, and there remains a limited understanding of the spatiotemporal patterns and predictors of the joint outcomes. We use a hierarchical Bayesian spatiotemporal multivariate Poisson regression model on data from (N=167) ZIP-codes between 2009 and 2014 in New York City...
Source: Spatial and Spatio-temporal Epidemiology - Category: Epidemiology Source Type: research
CONCLUSIONS: Medication-assisted treatment could be initiated in the emergency department following overdose for patients with opioid use disorder, and post-overdose protocols, such as naloxone provision and linkage to treatment and harm reduction services, have the potential to prevent future overdose for those at risk. PMID: 31639639 [PubMed - as supplied by publisher]
Source: Addictive Behaviors - Category: Addiction Authors: Tags: Addict Behav Source Type: research
CONCLUSIONS: Combining drug classes with alcohol prior to OD was common and associated with a higher likelihood of hospitalization. Overdose prevention efforts should address acute risks of alcohol ingestion with other drugs. PMID: 31596516 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
Acute drug poisoning due to accidental or self-damaging overdoses is responsible for 5-10% of emergency medical interventions in Germany. The treatment of asymptomatic to life-threatening courses requires extensive expertise. On the basis of a  selective l...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
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