Effectiveness and Adherence of Golimumab in Rheumatoid Arthritis

Condition:   Arthritis, Rheumatoid Intervention:   Drug: Golimumab Sponsor:   Peking Union Medical College Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

Related Links:

CONCLUSION: Ultrasound could be as sensitive and specific as contrast-enhanced MRI for the diagnosis of subclinical synovitis and tenosynovitis.
Source: Clinics - Category: General Medicine Source Type: research
One of the most important messages from the recent review is that diagnostic difficulty can occur as a result of clinical presentations of extrapulmonary tuberculosis that overlap with other conditions [1]. Conditions which can overlap with extrapulmonary manifestations of tuberculosis include extrapulmonary manifestations of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Immunoglobulin G4-Related Disease (IgG4-RD) and cryptococcal infection. In each of these disorders the extrapulmonary complications which occur may be indistinguishable from the extrapulmonary manifestations of tuberculosis.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research
There is increasing recognition of the role the microbiome plays in states of health and disease. Microbiome studies in systemic autoimmune diseases demonstrate unique microbial patterns in Inflammatory Bowel Disease, Rheumatoid Arthritis, and Systemic Lupus Erythematosus to a lesser extent, whereas there is no single bug or pattern that characterizes Multiple Sclerosis. Autoimmune diseases tend to share a predisposition for vitamin D deficiency, which alters the microbiome and integrity of the gut epithelial barrier. In this review, we summarize the influence of intestinal bacteria on the immune system, explore the microb...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 20 January 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Tatianna F.S. De Nardo, Paulo H.L. Bertolo, Priscila A. Bernardes, Danísio P. Munari, Gisele F. Machado, Luciana S. Jardim, Pamela R.R. Moreira, Mayara C. Rosolem, Rosemeri O. VasconcelosABSTRACTMacrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that is produced by many cell types in situations of homeostasis or disease. One of its functions is to act as a proinflammatory molecule. In humans, several studies have shown that MIF levels become elevated in the serum, urine, cerebrospinal flu...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
Source: Patient Preference and Adherence - Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
Human cytomegalovirus (HCMV) seropositivity has been associated with higher inflammation during rheumatoid arthritis (RA). However, no data are available on the impact of HCMV seropositivity on bone erosion pr...
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Research article Source Type: research
This article is protected by copyright. All rights reserved.
Source: Protein Science - Category: Biochemistry Authors: Tags: Article Source Type: research
AbstractPurpose of ReviewThe purpose of this review is to discuss the literature on associations between vitamin D and periodontal disease, including its strengths and weaknesses. Future direction for continued work in this area is provided.Recent FindingsResearch in cross-sectional cohorts, surveys, and case-control studies provide support for a role of vitamin D in periodontal disease, especially using clinical indicators such as bleeding on probing and clinical attachment loss. However, these studies have a number of limitations. They cannot establish temporality of these associations. Most case-control studies have bee...
Source: Current Oral Health Reports - Category: Dentistry Source Type: research
Publication date: Available online 18 January 2020Source: Joint Bone SpineAuthor(s): Codrina Ancuţa, Cristina Pomîrleanu, Claudia Mihailov, Rodica Chirieac, Eugen Ancuţa, Cristina Iordache, Codruţa Bran, Oana ȚănculescuAbstractObjective: Despite a widely recognized bidirectional pathobiologic relationship between rheumatoid arthritis (RA) and periodontal disease, the impact of innovative anti-rheumatic drugs in modulating not only inflammatory and immune articular damage, but also periodontal microenvironment remains debatable. We aimed to evaluate the periodontal status in RA with and without baricitinib, a Jan...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
The barrier between mind and body appears to be crumbling. Clinical practice and public perception need to catch upUnlikely as it may seem, #inflammation has become a hashtag. It seems to be everywhere suddenly, up to all sorts of tricks. Rather than simply being on our side, fighting infections and healing wounds, it turns out to have a dark side as well: the role it plays in causing us harm.It ’s now clear that inflammation is part of the problem in many, if not all, diseases of the body. And targeting immune or inflammatory causes of disease has led to a series of breakthroughs, from new treatments for rheumatoid ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Mental health Psychiatry Multiple sclerosis Depression Dementia Society Medical research Science UK news Alzheimer's Parkinson's disease Schizophrenia Source Type: news
More News: Arthritis | Hospitals | Research | Rheumatoid Arthritis | Rheumatology