A multinational observational study identifying primary care patients at risk of overestimation of asthma control

npj Primary Care Respiratory Medicine, Published online: 05 December 2019; doi:10.1038/s41533-019-0156-4A multinational observational study identifying primary care patients at risk of overestimation of asthma control
Source: npj Primary Care Respiratory Medicine - Category: Primary Care Authors: Source Type: research

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Publication date: Available online 28 January 2020Source: Respiratory Medicine Case ReportsAuthor(s): Silvia De Rosa, Gianlorenzo Golino, Claudio RoncoAbstractStatus asthmaticus is a life-threatening disorder that can manifest in dangerous levels of hypercapnia and acidosis. The use of extracorporeal carbon dioxide removal (ECCO2R) has been used successfully to control pH and PaCO2 in patients with acute severe asthma. The present report describes the use of this technology in near-fatal asthma with brain death, and awaiting organ harvest.The ProLUNG® system consists of a veno-venous hemoperfusion circuit with an artif...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Publication date: Available online 28 January 2020Source: Journal of EthnopharmacologyAuthor(s): Yu Wang, Yan-Jiao Chen, Cheng Xiang, Guang-Wei Jiang, Yu-Dong Xu, Lei-Miao Yin, Dong-Dong Zhou, Yan-Yan Liu, Yong-Qing YangAbstractEthnopharmacological relevanceStandard therapy for asthma, a highly heterogeneous disease, is primarily based on bronchodilators and immunosuppressive drugs, which confer short-term symptomatic relief but not a cure. It is difficult to discover novel bronchodilators, although potential new targets are emerging. Traditional Chinese Medicine (TCM) formulas have been used to treat asthma for more than ...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
BY JESSICA DAMASSA BioLum Sciences is introducing new chemistry that has the potential to completely change the way we test for respiratory illnesses, like asthma, and analyze blood samples to identify hypertension. CEO Edward Allegra talks through the science behind both their breath and blood tests, both of which are patent-pending and have the ability to completely bend the cost-curve when it comes to identifying and monitoring these two common chronic conditions. What’s next for the early-stage health startup? A range of applications to detect everything from COPD to lung cancer and more. Filmed at Bayer G...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Tech Jessica DaMassa WTF Health Asthma Bayer G4A Bayer G4A Signing Day BioLum BioLum Sciences Edward Allegra Hypertension Source Type: blogs
Conclusion: We found available, good quality BFC CE and appropriate-use articles; however, all had limitations. PMID: 31983228 [PubMed - as supplied by publisher]
Source: Journal of Comparative Effectiveness Research - Category: General Medicine Tags: J Comp Eff Res Source Type: research
Omalizumab is an anti-IgE monoclonal antibody (mAb) approved for the treatment of severe asthma and chronic spontaneous urticaria. Use of omalizumab is associated with reported side effects ranging from local skin inflammation at the injection site to systemic anaphylaxis. To date, the mechanisms through which omalizumab induces adverse reactions are still unknown. Here, we demonstrated that immune complexes formed between omalizumab and IgE can induce both skin inflammation and anaphylaxis through engagement of IgG receptors (FcγRs) in FcγR-humanized mice. We further developed an Fc-engineered mutant version o...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Are asthma patients who use inhaled corticosteroids at an increased risk for pneumonia and hospitalization?BMC Pulmonary Medicine
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news
Researchers note in a new study that current rates of asthma-related ER visits are more than twice as high in areas that were once redlined in eight California cities, despite the practice being relegated to history.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
AbstractPurpose of ReviewProgestogen hypersensitivity (PH) is a condition which typically occurs in women in childbearing years with a spectrum of symptoms ranging from urticaria with or without angioedema, dermatitis to systemic anaphylaxis. Herein, a clinical case of PH is presented followed by a discussion on the evaluation, diagnosis, and management of PH.Recent FindingsProgestogen hypersensitivity (a.k.a. “autoimmune progesterone dermatitis”) symptoms are associated with exogenous progestin exposure (e.g., contraceptive medicines, in vitro fertilization therapy) or endogenous progesterone from progesterone...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Human lung fibroblasts (HLFs) treated with the viral mimetic polyinosine-polycytidylic acid (poly I:C) form an extracellular matrix (ECM) enriched in hyaluronan (HA) that avidly binds monocytes and lymphocytes. Mast cells are important innate immune cells in both asthma and acute respiratory infections including respiratory syncytial virus (RSV); however, the effect of RSV on HA dependent mast cell adhesion and/or function is unknown. To determine if RSV infection of HLFs leads to the formation of a HA-enriched ECM that binds and enhances mast cell activity primary HLFs were infected with RSV for 48 h prior to leukocyte bi...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
SANTA ANA, Calif., Jan. 27, 2020 -- (Healthcare Sales &Marketing Network) -- Cognita Labs, a respiratory technologies company, announced U.S. Food and Drug Administration (FDA) clearance for CapMedic, world's first interactive digital inhaler sensor for ... Devices, Drug Delivery, FDA Cognita Labs, CapMedic, asthma, Chronic Obstructive Pulmonary Disease
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
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