Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial
Conditions: Fatty Liver, Nonalcoholic; Diabetes Mellitus, Type 2 Intervention: Diagnostic Test: Simple fibrosis scores and electronic reminder messages Sponsor: Chinese University of Hong Kong Recruiting
Conditions: Renal Function Disorder; Glucose Metabolism Disorders Interventions: Drug: Dapagliflozin 10 MG; Drug: Hydrochlorothiazide 12.5mg Sponsor: University of Pisa Active, not recruiting
A new study in JAMA Internal Medicine suggests barbershops may be a good place to test black men for type 2 diabetes and educate those with prediabetes because of their stature as community meeting places.
This study aimed to compare the therapeutic efficacy of metformin and other anti-hyperglycemic agents in hepatocellular carcinoma (HCC) patients with type 2 diabetes (T2D). MATERIALS: A systematic electronic search on keywords including HCC and different anti-hyperglycemic agents was performed through electronic databases including Medline and EMBASE. The primary outcome was the overall survival (OS). The secondary outcomes were the recurrence-free survival (RFS) and progression-free survival (PFS). RESULTS: Six retrospective cohort studies were included for analysis: Four studies with curative treatment for HCC (6...
Children at risk of developing type 2 diabetes may be identified early by a dysfunctional pancreatic beta-cell, according to a new study published inDiabetes Care.News Medical
TYPE 2 diabetes is a serious problem and a worldwide health epidemic. The condition is where the insulin the pancreas makes can't work properly and noticing this symptom in your feet could be a warning that you may be at risk. What is it?
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.9b06801
We report convergence of CNN-based metrics of regulatory function with conventional approaches to variant prioritization – genetic fine-mapping and regulatory annotation enrichment. We demonstrate that CNN-based analyses can refine association signals at T2D-associated loci and provide experimental validation for one such signal. We anticipate that these approaches will become routine in downstream analyses of GWAS.
AbstractPurpose of ReviewDiabetes is a common and prevalent medical condition as it affects many lives around the globe. Specifically, type-2 diabetes (T2D) is characterized by chronic systemic inflammation alongside hyperglycemia and insulin resistance in the body, which can result in atherosclerotic legion formation in the arteries and thus progression of related conditions called diabetic vasculopathies. T2D patients are especially at risk for vascular injury; adjunct in many of these patients, their cholesterol and triglyceride levels reach dangerously high levels and accumulate in the lumen of their vascular system.Re...
Molecules, Vol. 25, Pages 549: Adropin as A Fat-Burning Hormone with Multiple Functions—Review of a Decade of Research Molecules doi: 10.3390/molecules25030549 Authors: Jasaszwili Billert Strowski Nowak Skrzypski Adropin is a unique hormone encoded by the energy homeostasis-associated (Enho) gene. Adropin is produced in the liver and brain, and also in peripheral tissues such as in the heart and gastrointestinal tract. Furthermore, adropin is present in the circulatory system. A decade after its discovery, there is evidence that adropin may contribute to body weight regulation, glucose and lipid ...