Indian consensus on gastroesophageal reflux disease in adults: A position statement of the Indian Society of Gastroenterology

AbstractThe Indian Society of Gastroenterology developed this evidence-based practice guideline for management of gastroesophageal reflux disease (GERD) in adults. A modified Delphi process was used to develop this consensus containing 58 statements, which were generated by electronic voting iteration as well as face-to-face meeting and review of the supporting literature primarily from India. These statements include 10 on epidemiology, 8 on clinical presentation, 10 on investigations, 23 on treatment (including medical, endoscopic, and surgical modalities), and 7 on complications of GERD. When the proportion of those who voted either to accept completely or with minor reservation was 80% or higher, the statement was regarded as accepted. The prevalence of GERD in India ranges from 7.6% to 30%, being  
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research

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Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Pharmacy Source Type: forums
Hello everyone! I am an Oral &Maxillofacial surgeon trained in India and I am looking for fellowship opportunities in Sweden/Denmark. Most websites have very limited info in English. Can someone help me out with information/ guidance with the same? Thank you in advance
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: International Dental Source Type: forums
In conclusion, vonoprazan 10 mg daily is effective in improving GERD symptoms. Advanced age, obesity, erosive esophagitis, alcohol use and history of H. pylori eradication influence the resolution of GERD symptoms. Treatment with vonoprazan favorably affects gastrointestinal symptoms in patients with GERD.
Source: The Kaohsiung Journal of Medical Sciences - Category: Universities & Medical Training Source Type: research
Esophageal adenocarcinoma (EAC) is rapidly increasing in incidence in many Western societies, requires demanding treatment, and is associated with a poor prognosis, therefore preventive measures are highly warranted. To assess the opportunities for prevention, we reviewed the available literature and identified seven main potentially preventive targets. Preventive effects were found on the basis of medium-level observational evidence following treatment of gastroesophageal reflux disease (using both medication and surgery) and tobacco smoking cessation, which should be clinically recommended among exposed patients. Nonster...
Source: Cancer Prevention Research - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Esophageal adenocarcinoma (EAC) is rapidly increasing in incidence in many Western societies, requires demanding treatment, and is associated with a poor prognosis, therefore preventive measures are highly warranted. To assess the opportunities for prevention, we reviewed the available literature and identified seven main potentially preventive targets. Preventive effects were found on the basis of medium-level observational evidence following treatment of gastroesophageal reflux disease (using both medication and surgery) and tobacco smoking cessation, which should be clinically recommended among exposed patients. Nonster...
Source: Cancer Prevention Research - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Abstract Peptic ulcer disease (PUD) has been further decreased over the last decades along with decreasing prevalence of Helicobacter pylori‐associated PUD. A delayed H. pylori eradication has been associated with an increased risk of rehospitalization for complicated recurrent peptic ulcer and reemphasized the importance of eradication especially in patients with peptic ulcer bleeding (PUB). PUB associated with NSAID/aspirin intake and H. pylori revealed an additive interaction in gastric pathophysiology which favors the “test‐and‐treat” strategy for H. pylori in patients with specific ris...
Source: Helicobacter - Category: Gastroenterology Authors: Tags: Original Article Source Type: research
Conclusion Night-shift work is suggested to be a risk factor for erosive esophagitis. Avoidance of night-shift work and lifestyle modification should be considered for prevention and management of gastroesophageal reflux disease.
Source: International Archives of Occupational and Environmental Health - Category: Occupational Health Source Type: research
Background: The prevalence of gastroesophageal reflux disease (GERD) has increased in Japan since the end of the 20th century due to changes in environmental factors, such as a decreased infection rate of Helicobacter pylori and increased ability of acid secretion in the Japanese population. In 2013, the Japanese health insurance system started to cover eradication treatment for all patients infected with H. pylori to prevent gastric cancer, suggesting we may soon be able to completely eradicate this infection in Japan. Re-clarification of the clinical characteristics of GERD in Japan is therefore required in time covering...
Source: Digestion - Category: Gastroenterology Source Type: research
Proton pump inhibitors (PPIs) are a class of acid suppression medications that block gastric parietal cell acid production by irreversibly inhibiting the luminal H+/K+ adenylpyrophosphatase (ATPase).1 PPIs are used for a variety of conditions involving inflammation of the upper gastrointestinal tract in children, including gastroesophageal reflux disease, erosive esophagitis, gastric and duodenal ulcers, eosinophilic esophagitis, and Helicobacter pylori gastritis.2-4 Alternative uses for PPIs are increasing, and include treatment of various pediatric respiratory symptoms, sleep disorders, and even irritability or excessive crying in infants.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Medical Progress Source Type: research
Conclusions The presence of symptoms cannot be considered as a valuable guide to indicate endoscopy since the majority of endoscopic lesions were asymptomatic and not H. pylori-related.
Source: Obesity Surgery - Category: Surgery Source Type: research
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