Improvement of the Skin Barrier Function with Physiologically Active Substances.
In this study, the ability of CER precursors to increase the level of CERs in the SC and improve the skin barrier function was examined. Glucosylceramide and sphingomyelin liposomes were used as CER precursors and prepared with a thin-film method. The particle diameter and surface potential of glucosylceramide liposomes were 120.0 nm and -20 mV, while those of sphingomyelin liposomes were 153.3 nm and -11.4 mV, respectively. Transmission electron microscopy images showed that both liposomes were closed vesicles having a lamellar structure. These liposomes were applied from the SC side of a three-dimensional cultured human epidermis model, and the level of CERs in the epidermis was measured by high-performance thin-layer chromatography. In this study, the application of glucosylceramide or sphingomyelin liposomes increased the amount of CERs. In addition, the precursors of CERs were effective in improving the skin barrier function. PMID: 31787643 [PubMed - in process]
CONCLUSION: Oat bran supplementation was effective in improving triglyceride, total cholesterol and HDL-cholesterol levels, suggesting that it is a therapeutic option for cardiovascular risk control in patients with psychiatric disorders. PMID: 32490954 [PubMed - in process]
Publication date: Available online 3 June 2020Source: Food ChemistryAuthor(s): Chengsheng Jia, Xue Xia, Huiqi Wang, Muhoza Bertrand, Gang Chen, Xiaoming Zhang
This report describes prevalence of high total cholesterol among adults aged ≥20 years, by age group and sex during 2015-2018.
HIGH cholesterol doesn't produce any symptoms but it does hike your risk of developing heart disease so it is important to lower high cholesterol levels. Certain foods are particularly adept at lowering cholesterol, including a tasty snack.
Conclusions. LDL-C is the lipid fraction strongest associated with younger age of presentation of first MI. These results support the importance of controlling and treating LDL-C in prevention of premature MI. PMID: 32483990 [PubMed - as supplied by publisher]
Publication date: Available online 2 June 2020Source: Redox BiologyAuthor(s): Matias M. Vazquez, Maria V. Gutierrez, Sonia R. Salvatore, Marcelo Puiatti, Virginia Actis Dato, Gustavo A. Chiabrando, Bruce A. Freeman, Francisco J. Schopfer, Gustavo Bonacci
Resumo O objetivo deste artigo é avaliar efeitos de um protocolo misto de exercícios físicos sobre o risco cardiovascular (RCV), qualidade de vida e presença de sintomas depressivos em idosos hipertensos. Estudo longitudinal, prospectivo e quase-experimental com 48 idosos. Desenvolveu-se um protocolo de exercícios físicos d urante 16 semanas, segundo American College Sports of Medicine e foram realizadas avaliações antropométricas (peso, estatura, índice de massa corporal e circunferência da cintura) e bioquímicas (colesterol total, LDL-c, H...
The regulator has reduced the maximum retail price of a new class of drugs, including statins, diabetes drugs, cardiovascular and combination drugs. The revised prices will have an impact on the manufacturers of these formulations, including Sun Pharma and Zydus Healthcare.
(CNN) — Still taking a daily aspirin to ward off heart attacks? You might want to think again, according to a new review. Aspirin is still one of the most commonly used medications in the world, even though it’s no longer recommended as a preventative by many health authorities. There is no evidence that low-dose aspirin — less than 325 milligrams a day — should be taken by most adults in good cardiovascular health, according to a new review of existing research that published Wednesday in the British Journal of Clinical Pharmacology. The review, which focused on the risks and benefits of low-dose d...
Authors: Zhang C, Cai W, Zhao H, Zhu M, Cui J, Sun Z Abstract To compare the clinical efficacy of gastric bypass in obese patients with T2DM with different BMI. Serum leptin, adiponectin, triglyceride (TG), cholesterol (CHOL) were measured as the indicators to show clinical efficacy after laparoscopic gastric bypass surgery (LRYGB). For patients with high BMI and patients with low BMI, the therapeutic effect of LRYGB surgical diabetes is more significant. The postoperative remission rate of diabetes in the high BMI group was not correlated with the preoperative lipid metabolism index but was positively correlated w...