Improvement of the Skin Barrier Function with Physiologically Active Substances.

In this study, the ability of CER precursors to increase the level of CERs in the SC and improve the skin barrier function was examined. Glucosylceramide and sphingomyelin liposomes were used as CER precursors and prepared with a thin-film method. The particle diameter and surface potential of glucosylceramide liposomes were 120.0 nm and -20 mV, while those of sphingomyelin liposomes were 153.3 nm and -11.4 mV, respectively. Transmission electron microscopy images showed that both liposomes were closed vesicles having a lamellar structure. These liposomes were applied from the SC side of a three-dimensional cultured human epidermis model, and the level of CERs in the epidermis was measured by high-performance thin-layer chromatography. In this study, the application of glucosylceramide or sphingomyelin liposomes increased the amount of CERs. In addition, the precursors of CERs were effective in improving the skin barrier function. PMID: 31787643 [PubMed - in process]
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - Category: Drugs & Pharmacology Authors: Tags: Yakugaku Zasshi Source Type: research

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CONCLUSION: Oat bran supplementation was effective in improving triglyceride, total cholesterol and HDL-cholesterol levels, suggesting that it is a therapeutic option for cardiovascular risk control in patients with psychiatric disorders. PMID: 32490954 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research
Publication date: Available online 3 June 2020Source: Food ChemistryAuthor(s): Chengsheng Jia, Xue Xia, Huiqi Wang, Muhoza Bertrand, Gang Chen, Xiaoming Zhang
Source: Food Chemistry - Category: Food Science Source Type: research
This report describes prevalence of high total cholesterol among adults aged ≥20 years, by age group and sex during 2015-2018.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Adult Health Cholesterol Men's Health MMWR Morbidity & Mortality Weekly Report Women's Health Source Type: news
HIGH cholesterol doesn't produce any symptoms but it does hike your risk of developing heart disease so it is important to lower high cholesterol levels. Certain foods are particularly adept at lowering cholesterol, including a tasty snack.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusions. LDL-C is the lipid fraction strongest associated with younger age of presentation of first MI. These results support the importance of controlling and treating LDL-C in prevention of premature MI. PMID: 32483990 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Publication date: Available online 2 June 2020Source: Redox BiologyAuthor(s): Matias M. Vazquez, Maria V. Gutierrez, Sonia R. Salvatore, Marcelo Puiatti, Virginia Actis Dato, Gustavo A. Chiabrando, Bruce A. Freeman, Francisco J. Schopfer, Gustavo Bonacci
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Resumo O objetivo deste artigo é avaliar efeitos de um protocolo misto de exercícios físicos sobre o risco cardiovascular (RCV), qualidade de vida e presença de sintomas depressivos em idosos hipertensos. Estudo longitudinal, prospectivo e quase-experimental com 48 idosos. Desenvolveu-se um protocolo de exercícios físicos d urante 16 semanas, segundo American College Sports of Medicine e foram realizadas avaliações antropométricas (peso, estatura, índice de massa corporal e circunferência da cintura) e bioquímicas (colesterol total, LDL-c, H...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
The regulator has reduced the maximum retail price of a new class of drugs, including statins, diabetes drugs, cardiovascular and combination drugs. The revised prices will have an impact on the manufacturers of these formulations, including Sun Pharma and Zydus Healthcare.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
(CNN) — Still taking a daily aspirin to ward off heart attacks? You might want to think again, according to a new review. Aspirin is still one of the most commonly used medications in the world, even though it’s no longer recommended as a preventative by many health authorities. There is no evidence that low-dose aspirin — less than 325 milligrams a day — should be taken by most adults in good cardiovascular health, according to a new review of existing research that published Wednesday in the British Journal of Clinical Pharmacology. The review, which focused on the risks and benefits of low-dose d...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News aspirin CNN Source Type: news
Authors: Zhang C, Cai W, Zhao H, Zhu M, Cui J, Sun Z Abstract To compare the clinical efficacy of gastric bypass in obese patients with T2DM with different BMI. Serum leptin, adiponectin, triglyceride (TG), cholesterol (CHOL) were measured as the indicators to show clinical efficacy after laparoscopic gastric bypass surgery (LRYGB). For patients with high BMI and patients with low BMI, the therapeutic effect of LRYGB surgical diabetes is more significant. The postoperative remission rate of diabetes in the high BMI group was not correlated with the preoperative lipid metabolism index but was positively correlated w...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
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