Comparative analysis for the implication of serum cardiac troponin measurements by conventional versus high-sensitivity assays in patients with traumatic brain injury.

CONCLUSIONS: Although the positivity of any troponin assay is associated with high mortality post-TBI, the use of HsTnT relatively outperforms the conventional troponin assay for early risk stratification and detection of stress-induced myocyte injury in patients with TBI. Further studies are needed to support our findings. PMID: 31789007 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

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Feixia Zheng1*, Xiuyun Ye1, Xulai Shi1, Zhongdong Lin1, Zuqin Yang1 and Longxiang Jiang2* 1Department of Pediatrics, The Second Affiliated Hospital &Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China 2Department of Respiratory Medicine, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou, China Background: Hyponatremia has frequently been described as a common complication associated with bacterial meningitis, though its frequency and clinical course in children with bacterial meningitis are unclear. The present study aimed to investigate the frequen...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Publication date: Available online 15 December 2018Source: The Lancet NeurologyAuthor(s): Ralf Reilmann, Andrew McGarry, Igor D Grachev, Juha-Matti Savola, Beth Borowsky, Eli Eyal, Nicholas Gross, Douglas Langbehn, Robin Schubert, Anna Teige Wickenberg, Spyros Papapetropoulos, Michael Hayden, Ferdinando Squitieri, Karl Kieburtz, G Bernhard Landwehrmeyer, European Huntington's Disease Network, Pinky Agarwal, Karen E Anderson, Nasir A Aziz, Jean-Phillippe Azulay, Anne C Bachoud-LeviSummaryBackgroundPrevious trials have shown that pridopidine might reduce motor impairment in patients with Huntington's disease. The aim of this...
Source: The Lancet Neurology - Category: Neurology Source Type: research
DISCUSSION: Overall, the literature supports beneficial pleotropic effects of statin use in contrast-induced nephropathy, head injury, Alzheimer's and Parkinson's disease, nuclear cataract, prostate cancer, infection management, and spinal cord injury. Further investigation is warranted, and randomized clinical trials are needed to confirm the clinical utility suggested by the reported studies included in this meta-analysis. PMID: 30033872 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research
Objectives: Therapeutic hypothermia has been of topical interest for many years and with the publication of two international, multicenter randomized controlled trials, the evidence base now needs updating. The aim of this systematic review of randomized controlled trials is to assess the efficacy of therapeutic hypothermia in adult traumatic brain injury focusing on mortality, poor outcomes, and new pneumonia. Data Sources: The following databases were searched from January 1, 2011, to January 26, 2018: Cochrane Central Register of Controlled Trial, MEDLINE, PubMed, and EMBASE. Study Selection: Only foreign articl...
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research
This study was designed to assign a monetary cost (in Malaysian ringgits [RM]) to the treatment of patients with surgically treated isolated traumatic head injury as determined up to 1 year after injury. METHODS Relevant resource items used were identified and valued using the direct measurement of costs method, cost accounting methods, standard unit costs method, fees, charges and/or market prices method. These values were then tabulated to generate the total costs for each patient, via a combination of macro-costing and micro-costing methods. Malaysian currency values were converted to US dollars according to the average...
Source: Neurosurgical Focus - Category: Neurosurgery Authors: Tags: Neurosurg Focus Source Type: research
Conclusion: The modifiable factors affecting morbidity and mortality were identified. Mild to moderate chest injury due to blunt trauma is difficult to diagnose. The restoration of respiratory physiology has not only significant implications on recovery from chest injury but also all other injuries. It is our sincere hope that the score we have formulated will help reduce mortality and morbidity after further trials.
Source: Journal of Emergencies, Trauma and Shock - Category: Emergency Medicine Authors: Source Type: research
Conclusion Since senior citizens are susceptible to delirium due to several of its causes, it is important to focus on the preventable ones, so it doesn’t develop. Along with preventing delirium, eliminating some causes many also prevent some forms of dementia. What are your experiences in caring for loved ones with delirium or dementia? We encourage you to share with us in the comment section below.
Source: Shield My Senior - Category: Geriatrics Authors: Tags: Senior Safety Source Type: blogs
  As a school-based SLP, I usually celebrated Better Hearing and Speech Month (BHSM) by creating an activity to use with my students and a classroom lesson for teachers. But what about raising awareness with our co-workers? So this year, I created an activity I’m using with my ASHA co-workers and thought you might like to share it in your school, private practice, office, health care facility or community-based organization meeting during the month of May! This BHSM game is a takeoff on Family Feud. First, divide your group into “families.” Ask each family to determine their spokesperson. They can a...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - Category: Speech Therapy Authors: Tags: Advocacy Audiology Events Speech-Language Pathology Early Intervention hearing loss hearing protection Language Disorders Professional Development Swallowing Disorders Source Type: blogs
CONCLUSION: The disease entity of acute diffuse pulmonary hemorrhage is similar to neurogenic pulmonary edema. Physicians should be aware of this extremely rare but life-threatening complication, namely seizure-related acute diffuse pulmonary hemorrhage. The patient's response to respiratory support and corticosteroid is usually quite satisfactory. PMID: 27411798 [PubMed - in process]
Source: Acta Neurologica Taiwanica - Category: Neurology Tags: Acta Neurol Taiwan Source Type: research
Abstract Oropharyngeal dysphagia is a common condition after stroke, Parkinson’s disease (PD), and Alzheimer’s disease (AD), and can cause serious complications including malnutrition, aspiration pneumonia, and premature mortality. Despite its high prevalence among the elderly and associated serious complications, dysphagia is often overlooked and under-diagnosed in vulnerable patient populations. This systematic review aimed to improve understanding and awareness of the prevalence of dysphagia in susceptible patient populations. MEDLINE, EMBASE, the Cochrane library, PROSPERO, and disease-specific web...
Source: Dysphagia - Category: Speech Therapy Source Type: research
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