Effects of Artificial Sweeteners on Glucose Metabolism in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2 Intervention:   Dietary Supplement: sucralose Sponsors:   RenJi Hospital;   ShiBei Hospital , JingAn District, Shanghai;   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;   PuNan Hospital ,Shanghai Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Source: BMJ Comments - Category: General Medicine Source Type: forums
CONCLUSIONS Our results highlight that interaction of Nr4a1 and LKB1 can mitigate T2DM by activating the AMPK/SIRT1 signaling pathway and inhibiting NF-kappaB activation. This may offer new insight for T2DM treatment. PMID: 31939452 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Over 30 million people in the United States live with diabetes, and approximately 7.7 million people have diabetic retinopathy, making it the most common cause of vision loss in working-aged adults. The prevalence of diabetic retinopathy has increased significantly over the past 20 years, due to the rise in the number of people diagnosed with diabetes. How does diabetes affect the retina? The retina is the light-sensing component located in the back of the eye. It is composed of blood vessels, nerve cells (neurons), and specialized cells called photoreceptors that are involved in directly sensing light. The ability of the ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diabetes Eye Health Source Type: blogs
I have posted a number of notes pertaining to wearables and wearable health ecosystems (see, for example:Sony Develops Health Wearable Providing Connectivity, Stipulating That It's Not a Smartwatch;The Evolution of"Wearable Health Ecosystems" and Associated Partnerships;Status Reports and Hospital Referrals from Wearable Health Ecosystems). I have not yet raised the issue of providing a virtual personal assistant (VPS) with these home-based health systems. This idea was discussed in a recent article (see:Wearables Hold the Key to Connected Health Monitoring) and below is an excerpt from it:As voice inter...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: AI Health Wearable Healthcare Delivery Healthcare Innovations Medical Consumerism Point-of-Care Testing Public Health Test Kits and Home Testing Source Type: blogs
Authors: Traven SA, Synovec JD, Walton ZJ, Leddy LR, Suleiman LI, Gross CE Abstract INTRODUCTION: The purpose of this study is to investigate the current disparities for major lower extremity amputation in patients with critical limb ischemia (CLI) and infection. METHODS: A retrospective analysis of the National Surgical Quality Improvement Program's database for the years 2011 to 2017 was conducted. Multivariate models were used to isolate the effect of race and ethnicity on the likelihood of a below-knee or above-knee amputation (BKA and AKA, respectively) for CLI secondary to type 2 diabetes mellitus, athero...
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
Authors: Niguram P, Polaka SN, Rathod R, Kalia K, Kate AS Abstract Empagliflozin (EGF) received USFDA approval in 2014 for oral use to control the glucose levels in adults with type 2 diabetes mellitus. Albeit, a systematic drug-excipient compatibility study of EGF has not been reported in the open literature. As physical and chemical interactions affect the performance of the formulation, this study intended to unveil the drug and excipients interactions which would later help in development of a robust solid dosage form. Differential scanning calorimetry (DSC) was applied as a screening tool for the assessment of...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
TYPE 2 DIABETES is a British epidemic. Charity Diabetes UK reported there are 4.7 million people in the UK with diabetes, with that figure expected to grow to 5.5 million within the next decade. New scientific discoveries are always welcome in the battle against diabetes and, now, a recent study reveals another possible way to combat the illness.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
Conclusions: The present systematic review suggests that there are biologic bases to suggest that type 2 DM may act as a risk factor for developing an endodontic pathology, affecting the course of the disease in terms of susceptibility, prevalence, progression, and tissue healing capacity as a consequence of a disrupted immune response. However, more well-designed clinical investigations carrying out suitable research methodologies are needed to elucidate the influence of type 2 DM on the pulpal and periapical disease evolution.
Source: Quintessence International - Category: Dentistry Source Type: research
This study has led to the development of ongoing trials that will establish which patients will benefit most from this therapy, particularly with regard to comorbidities.ResumoA prevalência da diabetes mellitus tipo 2 (DMT2) continua a aumentar e a sua associação com a doença cardiovascular (CV) tem levado à incorporação e valorização de endpoints CV nos ensaios clínicos sobre o tratamento da DMT2.Este artigo faz uma revisão dos vários ensaios já realizados e em desenvolvimento, neste âmbito, com especial enfoque no estudo EMPA-...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
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