International view on genetic frontotemporal dementia

Publication date: Available online 3 December 2019Source: The Lancet NeurologyAuthor(s): Eline Wauters, Christine Van Broeckhoven
Source: The Lancet Neurology - Category: Neurology Source Type: research

Related Links:

Dementia is a global health problem, with the World Health Organization estimates placing the number of afflicted persons at around 50 million worldwide.1 Without a treatment or cure, projections are that numbers will increase dramatically around the world by 2050.2 The prevalent intervention strategy has been pursuit of a drug to cure this illness or to modify the illness course. Available medications, mainly approved for use in Alzheimer's-type dementia (AD) but extended empirically to other forms, are mainly palliative with only modest benefits in a subset of patients.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Tags: Editorial Source Type: research
Authors: Chosy EJ, Edland SD, Gross N, Meyer MJ, Liu CY, Launer LJ, White LR Abstract INTRODUCTION: The CAIDE (Cardiovascular Risk Factors, Aging, and Incidence of Dementia) dementia risk score is based on demographic, genetic, and modifiable risk factors in midlife and has been shown to be predictive of later-life dementia. OBJECTIVE: To test the predictive capacity of the CAIDE dementia risk score among a cohort of Japanese-American men. METHODS: Midlife measures were obtained from a sample of 3,582 Japanese-American men in the Honolulu Heart Program (1965-1968, average age = 53.1 years). A follow-up exam...
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
A Swedish study found that men and women with depression were much more likely to develop dementia than their peers without depression.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Depression (Mental) Mental Health and Disorders Dementia Source Type: news
Conditions:   Dementia;   Cognitive Impairment Interventions:   Behavioral: Functionally Tailored Oral Care Intervention;   Behavioral: Control Intervention Sponsors:   Xi Chen;   National Institutes of Health (NIH);   National Institute of Nursing Research (NINR) Not yet recruiting
Source: - Category: Research Source Type: clinical trials
The majority of doctors will tell you that there is nothing you can do to reverse fatty liver and that health problems such as cirrhosis and liver failure may be in your future that they will address with the awful “solution” of liver transplant. The truth is the opposite: fatty liver is easily and readily reversible in virtually everybody, provided you take action before irreversible changes take place and are given the right information and tools. In this video, I discuss the three basic phenomena that drive fat deposition, liver damage, and inflammation that lead to this condition: Carbohydrate consumption ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open bowel flora carbohydrates carbs Inflammation NAFLD nash triglycerides undoctored wheat belly Source Type: blogs
Depression is a common comorbidity in dementia. Randomised controlled studies of antidepressants do not show a significant improvement in depressive symptoms in patients with comorbid dementia and are known to lead to an increase in side effects. However, there are relatively few studies of depression in dementia, and drawing firm conclusions about the use of antidepressants is limited by the amount of data available. Furthermore, it is unclear whether data can be extrapolated from similar populations (eg, those with late-life depression) to inform pharmacotherapy in this patient group. Given the lack of effectiveness and ...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
AIM: The aims of this study were to create a scale for measuring the sedating and activating effects of drugs and to analyse if the total value of this scale correlates significantly with falls requiring medical treatment in dementia patients. Furthermore,...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
(University of British Columbia) Living near major roads or highways is linked to higher incidence of dementia, Parkinson's disease, Alzheimer's disease and multiple sclerosis (MS), suggests new research published this week in the journal Environmental Health.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
CONCLUSION: Regardless of the complexity in estimating the costs associated with informal caregiving in dementia, this paper provides some insights on the burden they can represent for the family income. PMID: 31962060 [PubMed - as supplied by publisher]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
To determine the efficacy of fall intervention programs in nursing homes (NHs) and the generalizability of these interventions to people living with cognitive impairment and dementia.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Tags: Original Study Source Type: research
More News: Brain | Dementia | Genetics | Neurology