A moderately extended time interval between hCG administration and oocyte retrieval is good for most patients with oocyte retrieval scheduled on the same day: a retrospective cohort study.
A moderately extended time interval between hCG administration and oocyte retrieval is good for most patients with oocyte retrieval scheduled on the same day: a retrospective cohort study. J Obstet Gynaecol. 2019 Dec 02;:1-6 Authors: Deng M, Liang Y, Qin H, Tan Y, Mai Q, Yuan X, Yuan Y Abstract Evidence is limited regarding the time intervals between human chorionic gonadotropin (hCG) administration and oocyte retrieval in controlled ovarian hyperstimulation cycles, and it is difficult to determine proper schedules to optimise outcomes for patients undergoing oocyte retrieval on the same day. We aimed to identify correlations between factors pertaining to treatment outcomes and time intervals to facilitate working schedules of ART centres. Our study included 2509 patients who underwent ICSI cycles. Based on different time intervals between hCG administration and oocyte retrieval, all cycles were divided into four groups: group 1 (34.00-35.99 hours), group 2 (36.00-36.99 hours), group 3 (37.00-37.99 hours) and group 4 (38.00-39.32 hours). Female age, basal FSH level, Gn starting stimulation dosage and total Gn dosage of group 1 were significantly higher than those of other groups. E2 level on hCG day and number of follicles aspirated were significantly higher in group 4 than in the other groups. Number of oocytes retrieved, oocyte retrieval rate, cleavage rate and number of usable embryos were positively correlated with the time...
Publication date: Available online 23 January 2020Source: Reproductive BioMedicine OnlineAuthor(s): Ryan D. Rose, Michael F. Barry, Emma V. Dunstan, Siu Man Yuen, Lyndal P. Cameron, Emma J. Knight, Robert J. Norman, Mary-Louise HullAbstractResearch QuestionDoes Embryogen®/BlastGen™ culture medium improve live birth rates compared to standard culture medium for women undergoing IVF/ICSI with poor prognosis.DesignRandomised clinical trial. 100 couples undergoing IVF/ICSI, were randomly allocated to having their inseminated oocytes incubated in either Embryogen®/BlastGen™ sequential culture media (Cooper S...
ConclusionsThe rate of successful TESE and the ICSI outcome in cancer survivors with NOA and RE/FOE is the same as non-cancer azoospermic patients. Female partner age (older than 40 years) was associated with a significant reduction in live birth rates after TESE-ICSI procedures.
ConclusionsThe quantity of TQBs available for transfer or cryopreservation can provide important predictors for pregnancy and live birth after the first embryo transfer cycle with a single blastocyst. This valuable information may assist with the future application of SBT.
CONCLUSIONS: TAI had no impact on ovarian reserve in euthyroid women and had no association with IVF/ICSI outcomes in women with DOR. Although an increased incidence of congenital anomalies in the positive TAI group was observed in women with NOR, the association between neonatal anomalies and TAI cannot be concluded. Large cohort studies to evaluate the effects of TAI on offspring health are warranted, and further experimental studies are required to explore the underlying mechanisms. PMID: 31928166 [PubMed - as supplied by publisher]
This study suggests that human blastocysts that collapse spontaneously during development are less likely to implant and generate a pregnancy compared with embryos that do not. Although this is a retrospective study, the results demonstrated the utility of collapse episodes as new marker of embryo selection following eSET at blastocyst stage. PMID: 31928572 [PubMed - as supplied by publisher]
CONCLUSIONS: While avoiding unnecessary embryo transfers and miscarriages are important goals, patients and doctors need to be aware of the high cost implications of applying PGT-A using aCGH on polar bodies. FUNDING: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The ESTEEM study was funded by the European Society for Human Reproduction and Embryology. Illumina provided microarrays and other consumables necessary for aCGH testing of polar bodies. PMID: 31930663 [PubMed - as supplied by publisher]
ConclusionsAOA was able to “rescue” the poor reproductive outcomes in certain types of infertile couples with history of failure pregnancy.
CONCLUSION: MCDA twins after IVF/ICSI have lower overall survival rates and higher rates of second-trimester miscarriage compared to spontaneously conceived MCDA twins. This article is protected by copyright. All rights reserved. PMID: 31909558 [PubMed - as supplied by publisher]
CONCLUSIONS: UtA-PI and proportion of SGA are lower in pregnancies after frozen as compared to fresh blastocyst transfer. This article is protected by copyright. All rights reserved. PMID: 31909549 [PubMed - as supplied by publisher]
ConclusionsChromosomal aberrations and aneuploidy manifested specific characteristics that differed between TEs and SA-CVBs, which indicates that distinct chromosomal abnormalities can affect certain developmental stages of embryos. Further analysis is needed to explore the chromosomal mechanisms affecting embryo development and implantation. Such information will help clinical assessments in prenatal diagnosis and reduce the incidence of genetically abnormal fetuses.