An analysis of MRI derived cortical complexity in premature-born adults: Regional patterns, risk factors, and potential significance

Publication date: Available online 4 December 2019Source: NeuroImageAuthor(s): Dennis M. Hedderich, Josef G. Bäuml, Aurore Menegaux, Mihai Avram, Marcel Daamen, Claus Zimmer, Peter Bartmann, Lukas Scheef, Henning Boecker, Dieter Wolke, Christian Gaser, Christian SorgAbstractPremature birth bears an increased risk for aberrant brain development concerning its structure and function. Cortical complexity (CC) expresses the fractal dimension of the brain surface and changes during neurodevelopment. We hypothesized that CC is altered after premature birth and associated with long-term cognitive development.One-hundred-and-one very premature-born adults (gestational age
Source: NeuroImage - Category: Neuroscience Source Type: research

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Chances are you know someone who was born prematurely. According to the Centers for Disease Control and Prevention, the rate of preterm births is going up. Last year, one in 10 American babies was born before 37 weeks gestation. Author Sarah DiGregorio ("Early: An Intimate History of Premature Birth and What It Teaches Us About Being Human") talks about one of the biggest public health threats facing this country.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
One in 10 births in this country is premature, one of the highest rates in the industrialized world; author Sarah DiGregorio says we must do better
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
(RMIT University) A new therapy being developed by a group of researchers from across the globe aims to see if stem cells can be used to regenerate the brain damage caused by premature birth. This brain damage is called 'encephalopathy of prematurity' (EOP). The European research project, which is called PREMSTEM, has received € 9M in funding from the European Union's prestigious Horizon 2020 Research and Innovation programme.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Conclusions: Brazil has an increasing tendency for cleft lip and/or cleft palate (p=0.019), reinforcing the need to strengthen health care networks, providing adequate support for newborn with cleft lip and/or cleft palate and their families.Resumo Objetivos: analisar a tend ência e os fatores associados à presença de fissura labial e/ou fenda palatina em recém-nascidos brasileiros, a fim de verificar possíveis associações da mesma com fatores maternos, assistenciais e do recém-nascido. Métodos: estudo transversal, ecológico, envolvendo todos os nasciment...
Source: Revista Brasileira de Saude Materno Infantil - Category: Midwifery Source Type: research
In conclusion, differences in incidence and spectrum of full-term and premature births we obtained in NICU will provide diagnostic guidelines and therapeutic clues of neonatal IEMs for pediatricians.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Prolonged neonatal oxygen exposure causes persistent aortic structural and biomechanical alterations, which was even more pronounced after recovery in normoxia. This was accompanied by a marked impairment in left ventricular function. These findings have important implications as it suggests that premature babies exposed to oxygen may be predisposed to vascular dysfunction, leading to increased risk of cardiovascular disease in later life. As this affected population begins to age, there will be a critical need to identify the underlying pathophysiological mechanisms for these vascular morbidities in preterm survivors. Abs...
Source: Physiological Reports - Category: Physiology Authors: Tags: ORIGINAL RESEARCH Source Type: research
CONCLUSION: Regardless of COS protocols, FET could be performed immediately after a freeze-all strategy for delaying FET failed to improve reproductive and neonatal outcomes. PMID: 31924215 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Prolonged neonatal oxygen exposure causes persistent aortic structural and biomechanical alterations, which was even more pronounced after recovery in normoxia. This was accompanied by a marked impairment in left ventricular function. These findings have important implications as it suggests that premature babies exposed to oxygen may be predisposed to vascular dysfunction, leading to increased risk of cardiovascular disease in later life. As this affected population begins to age, there will be a critical need to identify the underlying pathophysiological mechanisms for these vascular morbidities in preterm survivors. Abs...
Source: Physiological Reports - Category: Physiology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Intrauterine Growth Restriction (IUGR) affects 8% of newborns and increases morbidity and mortality for the offspring even during later stages of life. Single omics studies have evidenced epigenetic, genetic, and metabolic alterations in IUGR, but pathogenic mechanisms as a whole are not being fully understood. An in-depth strategy combining methylomics and transcriptomics analyses was performed on 36 placenta samples in a case-control study. Data-mining algorithms were used to combine the analysis of more than 1,200 genes found to be significantly expressed and/or methylated. We used an automated text-mining approach, usi...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Masimo has won FDA clearance for its RD SET sensors, that feature the company’s signature Measure-through Motion and Low Perfusion SET pulse oximetry, to sport much better oxygen saturation (SpO2) accuracy specs when monitoring neonatal patient...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Critical Care Ophthalmology Pediatrics Source Type: blogs
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