Integrating data of veterinarians’ practices in assessing the cost effectiveness of three components of the bovine tuberculosis surveillance system by intradermal tuberculin testing in French cattle farms through a scenario-tree approach
Publication date: Available online 3 December 2019Source: Research in Veterinary ScienceAuthor(s): V. Gétin-Poirier, G. Crozet, S. Gardon, B. Dufour, J. RivièreAbstractDisease surveillance systems’ effectiveness relies on participants following prescribed practices. We developed a general method to improve a previous cost-effectiveness evaluation of three French screening program protocols for bovine tuberculosis (bTB) to account for the practices of participants by scenario tree modelling. This method relies on: 1) semi-directive interviews of participants to identify the variability of practices and potentially influential factors, and to understand the sociological context; 2) a quantitative survey, based on multiple-choice questions, to quantify various practices and identify significantly influential factors by multivariable regression analyses; 3) addition of the scenario-tree nodes corresponding to the practices and their influential factors and configuration of the new limbs according to the data of the quantitative survey.We used this approach to integrate data concerning veterinary practices and identify some failures to conform to regulatory guidelines regarding intradermal cervical comparative tuberculin test (SICCT) (testing and notification of non-negative results). Such nonconformities appeared to be mainly caused by cattle restraint issues and the perception of veterinarians of the bTB control program. Indeed, their perception of that progr...
[East African] The Global Fund, the body that finances the world's HIV, tuberculosis (TB) and malaria programmes, has given Kenya Ksh42 billion ($420 million) to cover the intervening years to 2024.
Publication date: Available online 20 January 2020Source: International Journal of PaleopathologyAuthor(s): Elizabeth A. Nelson, Jane E. Buikstra, Alexander Herbig, Tiffiny A. Tung, Kirsten I. BosAbstractAndean paleopathological research has significantly enhanced knowledge about the geographical distribution and evolution of tuberculosis (TB) in pre-Columbian South America. In this paper, we review the history and progress of research on ancient tuberculosis (TB) in the Andean region, focusing on the strengths and limitations of current approaches for the molecular detection of ancient pathogens, with special attention to...
This study reports the validation of an enzyme-linked immunosorbent assay (ELISA) to detect bovine tuberculosis as an ancillary test to TST in dairy farms in Argentina.The estimated validation parameters were within the established requirements of the World Organization for Animal Health (OIE). The test demonstrated high repeatability, with coefficients of variation
ConclusionMore effective thromboprophylaxis and pre-test assessment is necessary for EOC patients. For prediction VTE events, D-dimer levels (>4.215 μg/ml) were the independent predictors before operation. Age and debulking surgery were the independent predictors post operation.
Conclusion: For uveitis of unknown cause, diagnostic PPV is an effective, reliable, and relatively safe procedure for establishing the definite diagnosis and guiding further treatment. Positive therapeutic effect could also be achieved.
Only three new treatments available in 10 or more poorer countries, report findsMany antibiotics are unavailable in poorer countries despite higher infection rates, exacerbating the threat of drug-resistant superbugs, according to a report to bepresented to world leaders and the bosses of top pharmaceutical companies in Davos.The report, released by the Access to Medicine Foundation, an Amsterdam-based non-profit group, also shows that the number of new treatments being developed for common infectious diseases such as pneumonia, tuberculosis and gonorrhoea has fallen.Continue reading...
New research in macaques finds that changing the delivery method of an existing tuberculosis vaccine can drastically improve its efficacy.
[Daily Maverick] Overcrowding, understaffing and poor hygiene are said to be the main reasons for the deaths of the 10 newborns at Tembisa Hospital.