Polymorphism existence of mobile tigecycline resistance gene tet(X4) in Escherichia coli.

Polymorphism existence of mobile tigecycline resistance gene tet(X4) in Escherichia coli.
Antimicrob Agents Chemother. 2019 Dec 02;:
Authors: Song H, Liu D, Li R, Fu Y, Zhai W, Liu X, He T, Wu C, Bai L, Wang Y
Abstract
Recently, two novel plasmid-mediated tigecycline resistance genes, tet(X3) and tet(X4), have been identified in Acinetobacter baumannii and Escherichia coli, respectively, both of which can significantly compromise the efficacy of tigecycline (1-3), which is one of the few available drugs that can be used to treat infections caused by extensively drug-resistant pathogens (4).….
PMID: 31791944 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - December 1, 2019 Category: Microbiology Authors: Song H, Liu D, Li R, Fu Y, Zhai W, Liu X, He T, Wu C, Bai L, Wang Y Tags: Antimicrob Agents Chemother Source Type: research