Lower proportion of CD19+IL-10+ and CD19+CD24+CD27+ but not CD1d+CD5+CD19+CD24+CD27+ IL-10+ B cells in children with autoimmune thyroid diseases.

Conclusions: Our data demonstrate that the reduction in the number of Bregs with CD19+CD24+CD27+IL-10+ and CD19+IL-10+ expression could be responsible for breaking immune tolerance and for AITD development in children. PMID: 31790305 [PubMed - as supplied by publisher]
Source: Autoimmunity - Category: Allergy & Immunology Tags: Autoimmunity Source Type: research