TAMEST names top rising STEM scientists of Texas in 2020 O'Donnell Award announcement

(The Academy of Medicine, Engineering&Science of Texas) Changing the future of Alzheimer's Disease. Utilizing crystals to produce drugs for kidney stones and malaria. Understanding previously unobserved functions of our universe. And pioneering the evolution of wound care. These are the discoveries by Texas' rising stars in research being honored with the 2020 Edith and Peter O'Donnell Awards by TAMEST.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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Conclusion: This paper features an autonomous, portable, 1-min analysis time, and low-cost per test device, without the need for samples, centrifugation, allowing the use of whole blood. Significance: The presented device is a step ahead for meeting the growing clinical demands for reliable, rapid, portable, and quantitative malaria diagnosis.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Publication date: Available online 20 January 2020Source: NeurocomputingAuthor(s): Wei Li, Xuefeng Lin, Xi ChenAbstractApplying machine learning methods to various modality medical images and clinical data for early diagnosis of Alzheimer's disease (AD) and its prodromal stage has got lots of significant results. So far, the image data input to classifier mainly focus on 2D or 3D images. Although some functional imaging technologies, such as functional magnetic resonance imaging (fMRI), generate 4D data which contain both spatial and time-varying information of the brain, for the lack of suitable 4D image processing algori...
Source: Neurocomputing - Category: Neuroscience Source Type: research
Despite a 30% decline in mortality since 2000, malaria still affected 219 million subjects and caused 435,000 deaths in 2017. Red blood cells (RBC) host Plasmodium parasites that cause malaria, of which Plasmodium falciparum is the most pathogenic. The deformability of RBC is markedly modified by invasion and development of P. falciparum. Surface membrane area is potentially impacted by parasite entry and development, the cytoskeleton is modified by parasite proteins and cytosol viscosity is altered by parasite metabolism. RBC hosting mature parasites (second half of the asexual erythrocytic cycle) are abnormally stiff but...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Very early research suggests a novel, noninvasive brain stimulation technique guided by ultrasound may improve memory in Alzheimer's disease.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Psychiatry News Source Type: news
The J.P. Morgan Healthcare conference runs every year in San Francisco, a big draw for the biotech industry, and many organizations take the opportunity to host events at the same time. Among these, the SENS Research Foundation has for the past few years hosted a pitch day in which biotech companies in the longevity industry, largely startups, present to that portion of the Bay Area investor community interested in funding the treatment of aging as a medical condition. I was there to present on progress at Repair Biotechnologies, and took some notes on the other companies as they talked about their work. Kimera Labs ...
Source: Fight Aging! - Category: Research Authors: Tags: Investment Source Type: blogs
Publication date: Available online 20 January 2020Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Li Kong, Edgar Dawkins, Frederick Campbell, Edith Winkler, Rico J.E. Derks, Martin Giera, Frits Kamp, Harald Steiner, Alexander KrosAbstractThe biophysical properties and biological functions of membranes are highly dependent on lipid composition. Supplementing cellular membranes with very long chain fatty acids (vlcFAs) is notoriously difficult given the extreme insolubility of vlcFAs in aqueous solution. Herein, we report a solvent-free, photochemical approach to enrich target membranes with vlcFA. To pr...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
Our study aimed at the development of a method based on ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-ESI-MS) using selected ion monitoring for the simultaneous quantitation of the alkaloids galantamine, pseudolycorine, sanguinine and narciclasine in Amaryllidaceae species (Hippeastrum elegans, Habranthus cf. irwinianus, Hymenocallis littoralis and Griffinia nocturna). The alkaloids were extracted from dried and ground bulbs (100 mg) using liquid-liquid microextraction followed by solid phase extraction in cation exchange cartridges. The quantification method showed good linearity (correlation ...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
Not in person, as both are rather historical, but when in Paris, I encountered:Dr Alphonse LaveranandDr Paul GachetDr Laveran has a square named after him, adjacent to the Ecole de Val de Grace, a school of military medicine, where he worked after serving in the army as a physician, and where his father had held the same post.   Paris is good at telling you who a street is named after, so the street sign tells you he was the first French winner of theNobel Prize for Medicine or Physiology.  He won it for identifying both malaria and sleeping sickness as caused by parasites.Dr Gachet has aportrait in the...
Source: Browsing - Category: Databases & Libraries Source Type: blogs
Wearable technology allows an in-depth analysis of gait behaviour in free-living environments. This investigation aimed to use Alzheimer's disease as an example to apply the time series analysis technique of Statistical Parametric Mapping (SPM) to create d...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Myelin is the sheathing of nerves, essential to their function. Excessive loss produces disabling and ultimately fatal conditions such as multiple sclerosis, but we all lose myelin integrity to some degree as a consequence of the damage and dysfunction of degenerative aging. This most likely contributes to cognitive decline and other age-related issues. A number of different approaches have been identified to boost the operation of the normal maintainance processes that remyelinate nerves, such as FGF21 upregulation, or increasing the size of remyelinating cell populations. Here, researchers discover another possible trigg...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
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