Comparative study of the chemical composition and biological potential of honey from different regions of Serbia

Publication date: January 2020Source: Microchemical Journal, Volume 152Author(s): Svetlana Đogo Mračević, Marko Krstić, Aleksandar Lolić, Slavica RažićAbstractA chemical characterization and biological activity of 7 honey types (multifloral, linden, rapeseed, sunflower, phacelia, acacia and honeydew honey) from different regions of Serbia were presented. The physicochemical characteristics, mineral content, antioxidant and antimicrobial activity were estimated and discussed. All honeys showed good nutritional characteristics, according to the adopted criteria of the standard codex for honey. The concentrations of 15 elements in honey samples were determined using inductively coupled plasma optical emission spectroscopy (ICP-OES). Limits of quantification were in the range from 0.003 mg/kg (Cd, Cr, Cu, Mn, and Pb) to 1.50 mg/kg for sodium. Precision was expressed as relative standard deviation and its values were lower than 1.50%. Accuracy was evaluated with certified reference material (fish protein, DORM 4, NRC and cooking chocolate, SRM 2384, NIST) and obtained recovery percentages were 71-127%. The content of the most abundant elements (K, Mg, and Na) and microelements (Al, Cu, Fe, Mn, Ni, Se, Si, and Zn) showed a significant variability in accordance of their botanical and geographical origin, but also the influence of harvest conditions. The levels of toxic metals (As, Cd, Cr, and Pb) are much lower than the maximal allowed for these metals according to European C...
Source: Microchemical Journal - Category: Chemistry Source Type: research

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ConclusionThis is the first report on the synthesis of two novel ginsenosides, namely, glucosyl ginsenoside Rh2 and diglucosyl ginsenoside Rh2 from Rh2 by using recombinant GT isolated from L. rhamnosus. Moreover, diglucosyl ginsenoside Rh2 might be a new candidate for treatment of inflammation, obesity, and skin whiting, and especially for anticancer.
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
Authors: Crapé L, Strubbe B, Cesmeli E, de Clerck F Abstract A 24-year-old male presented with abdominal pain, postprandial vomiting and weight loss. Lab results showed an elevated serum eosinophil count and CT-scan demonstrated a thickened antral, duodenal and jejunal wall. Repetitive endoscopic mucosal biopsies were normal. Work-up of eosinophilia-associated gastro-intestinal disorders excluded secondary causes. Bone marrow showed an elevated eosinophil count without arguments for a primary hypereosinophilic syndrome. Endoscopic ultrasound-guided fine needle biopsy detected a strongly elevated number of eo...
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
Publication date: Available online 17 January 2020Source: Veterinary ParasitologyAuthor(s): Pengfei Zhao, Yuncan Li, Yanqin Zhou, Junlong Zhao, Rui FangAbstractEimeria tenella, belonging to protozoon, is the causative agent of cecal coccidiosis in chicken and causes enormous impacts for poultry industry. The surface antigens of apicomplexan parasites function as attachment and invasion in host-parasite interaction. Meanwhile, host immune response is triggered as a result of parasitic invasion. Immunogenicity and potency as a vaccinal candidate antigen of E. tenella surface antigen 4 (EtSAG4) have been unknown. Therefore, a...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Publication date: Available online 17 January 2020Source: Methods in MicrobiologyAuthor(s): Hongsheng Huang, Philippe Raymond, Chris Grenier, Jessica FaheyAbstractCampylobacter species, particularly thermotolerant Campylobacter spp., such as C. jejuni, are major human foodborne pathogens worldwide. Culture methods are routinely used for the detection of this organism. Campylobacter-like colonies can be difficult to identify on agar plates overgrown with competitive bacteria. An alternative, simple and rapid confirmation testing without further tedious biochemical tests would be useful. Previously we developed a colony blot...
Source: Methods in Microbiology - Category: Microbiology Source Type: research
Publication date: Available online 17 January 2020Source: Process BiochemistryAuthor(s): Junmei Hu, Gudong Li, Chaoqun Liang, Saira Shams, Shaozhou Zhu, Guojun ZhengAbstractBioreduction catalyzed by alcohol dehydrogenase/reductase is one of the most valuable biotransformation processes widely used in industry. The (S)-2-Chloro-1-(3, 4-difluorophenyl) ethanol is a key chiral synthon for synthesizing the antithrombotic agent ticagrelor. Herein, a new alcohol dehydrogenase (named Rhky-ADH) identified from Rhodococcus kyotonensis by an enzyme promiscuity-based genome mining method was successfully cloned and functionally expre...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
Publication date: Available online 17 January 2020Source: Journal of Hazardous MaterialsAuthor(s): Pengli Yu, Yajing Han, Donglin Han, Xiangmei Liu, Yanqin Liang, Zhaoyang Li, Shengli Zhu, Shuilin WuAbstractSome new kinds of antibiotics-free antibacterial agents are required to deal with bacterial infections due to the occurrence of drug-resistance. In this work, Cu-based metal-organic framework (HKUST-1) embedded with CuS NPs were fabricated via a simple in-situ sulfuration process. The synthesized MOFs exhibited an highly effective disinfection efficacy of 99.70% and 99.80% against Staphylococcus aureus and Escherichia c...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
Publication date: Available online 18 January 2020Source: Wound MedicineAuthor(s): Sara S. Abou Zekry, Ahmed Abdellatif, Hassan M.E. AzzazyAbstractHoney, pomegranate peel extract and bee venom, were used in combination with polyvinyl alcohol to develop a novel nanofibrous wound dressing. Methanolic pomegranate peel extract was prepared and mixed with either Manuka honey or lyophilized multiflora honey powder together with bee venom. The formulas were tested for their antibacterial activity, cytotoxicity, and wound healing activity in an excisional wound rat model. Scanning electron microscopy showed that lyophilized honey ...
Source: Wound Medicine - Category: General Medicine Source Type: research
In conclusion, our study provides evidence that BBR regulates fecal metabolites to ameliorate 5-Fu induced intestinal mucositis by modifying gut microbiota.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Her words hung in the hushed air.“Thank you for saving our boy,” the mother said, her voice choked by emotion.Devra Schwartz, and her husband, Jeff, recently had a chance to express their gratitude to eight of the 100 strangers whose blood donations provided a lifeline for their son, Judah, now 4. The Santa Monica youngster nearly died last year when his kidneys failed due to foodborne E. coli infection.Toxins in the E. coli bacteria ruptured Judah ’s red blood cells, leading to massive blood loss. His platelets — critical to clotting and preventing hemorrhage — plummeted to 13,000. A healthy ...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
ConclusionsST10 is considered as a high-risk clone worldwide. This type of mcr-1-harbouring clone is a major concern for human and animal health and must be under close surveillance. This study detected the presence of mcr-1 for the first time in Uruguay, albeit in an allodemic manner, associated with different antibiotic-resistance genes and from diverse clinical contexts. Considering that colistin is often the last therapeutic option available for multidrug-resistant Gram-negative bacilli infections, it is important to maximise precautions to avoid dissemination of isolates carrying mcr-1.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
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