Mobile stroke units could expedite treatment and improve patient outcomes in urban areas
(American Heart Association) Stroke patients received time-sensitive, lifesaving treatment approximately 30 minutes faster via an ambulance specially designed to treat stroke called a Mobile Stroke Unit (MSU).Patients diagnosed and treated in an MSU received stroke care faster, even in a densely populated city such as New York City, where this study was conducted.
Publication date: Available online 21 January 2020Source: SeizureAuthor(s): Petra Redfors, Lukas Holmegaard, Annie Pedersen, Christina Jern, Kristina MalmgrenAbstractPurposeTo assess long-term incidence and predictors of post-stroke epilepsy (PSE) and to evaluate the antiepileptic drug (AED) treatment in a well characterized cohort of middle-aged patients.MethodsThe study is based on the Sahlgrenska Study on Ischemic stroke, and included 1066 adult patients with first-ever or recurrent acute ischemic stroke (AIS) before the age of 70. Early seizures (ES) were defined as seizures within one week and PSE as unprovoked seizur...
Condition: Stroke (CVA) or TIA Interventions: Drug: Angong Niuhuang Wan; Drug: Angong Niuhuang Wan Placebo Sponsor: Chinese University of Hong Kong Recruiting
Conditions: Ischemic Stroke; Cognitive Impairment; Outcome, Fatal Intervention: Diagnostic Test: Montreal Cognitive Assessment (MoCA) Sponsor: Mansoura University Hospital Completed
CONCLUSION: The prevalence of carotid plaque was very high in the high-risk stroke population in southwestern China. Variants in genes involved in the endothelial function and inflammation were associated with the carotid plaque. The high-risk interactive genotype among rs7923349, rs1991013, rs1609682, and rs8081248 was independently associated with a higher risk of vulnerable plaque. PMID: 31956237 [PubMed - as supplied by publisher]
This study compared the risks of ischemic stroke/systemic embolism (ISSE) and major bleeding in patients with NVAF and stage IV-V CKD treated with rivaroxaban or warfarin.MethodsPatients with NVAF and stage IV-V CKD who initiated rivaroxaban or warfarin treatment between November 2011 and June 2018 were selected from the Optum® Deidentified EHR Database. Propensity score (PS)-matching was used to balance rivaroxaban and warfarin patients on 112 measured baseline covariates. ISSE and major bleeding events over two years following treatment initiation were ascertained with validated endpoint definitions. Outcomes were an...
Authors: Oshita J, Okazaki T, Mitsuhara T, Imura T, Nakagawa K, Otsuka T, Kurose T, Tamura T, Abiko M, Takeda M, Kawahara Y, Yuge L, Kurisu K Abstract We analyzed the cell characteristics, neuroprotective, and transplantation effects of human cranial bone-derived mesenchymal stem cells (hcMSCs) in ischemic stroke model rats compared with human iliac bone-derived mesenchymal stem cells (hiMSCs). The expressions of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF ) as neurotrophic factors were analyzed in both MSCs. hiMSCs or hcMSCs were intravenously administered into ischemic st...
CONCLUSION: The results suggest that a therapeutic approach integrating myoelectric bracing yields highly comparable outcomes to those derived from RTP-only. Myoelectric bracing could be used as alternative for labour-intensive upper extremity training due to its equivalent efficacy to hands-on manual therapy [AQ1] with moderately impaired stroke survivors. PMID: 31960066 [PubMed - as supplied by publisher]
A new national clinical director has suggested it is unlikely a key long-term plan commitment over stroke care will be met, which could leave thousands of people severely disabled.
Despite the pervasiveness of regret, doctors often overlook it.