Is vitamin D deficiency related to a higher risk of hospitalization and mortality in veterans with heart failure?

Vitamin D deficiency (25(OH)D) is a common finding in patients with congestive heart failure (HF) [1]. Vitamin D might play a role in the pathogenesis of HF [1 –4], with mechanisms for this possibly including effects on the renin–angiotensin system, insulin secretion and sensitivity, protection against angiogenesis and reduction of the pro-inflammatory response in HF [5–7]. However, a recent vitamin D supplementation trial did not find a beneficial e ffect on parameters of renin-angiotensin system in patient with advance HF [8].

Source: Maturitas - December 2, 2019 Category: Primary Care Authors: Raquel Aparicio-Ugarriza, Douglas Salguero, Yaqub Nadeem Mohammed, Juliana Ferri-Guerra, Dhanya J Baskaran, Seyed Abbas Mirabbasi, Alexis Rodriguez, Jorge G. Ruiz Source Type: research