High cholesterol may increase risk for heart disease in younger people, too

Researchers report in a new study that while that heart disease risk is higher than thought for younger people with high cholesterol, earlier intervention appears to mitigate this increased risk.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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FRIDAY, Oct. 9, 2020 -- Prescriptions of cholesterol-lowering statins for heart disease patients rose significantly when doctors were prompted to choose whether or not to order them, according to a new study. It included 82 cardiologists and more...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Purpose of review High-protein intake is commonly recommended to help people manage body weight. However, high-protein intake could have adverse health consequences. Here we review the latest findings concerning the effect of high-protein intake on cardiometabolic health. Recent findings Calorie-reduced, high-protein, low-carbohydrate diets lower plasma glucose in people with type 2 diabetes (T2D). However, when carbohydrate intake is not markedly reduced, high-protein intake often does not alter plasma glucose and increases insulin and glucagon concentrations, which are risk factors for T2D and ischemic heart disease...
Source: Current Opinion in Clinical Nutrition and Metabolic Care - Category: Nutrition Tags: NUTRITION AND PHYSIOLOGICAL FUNCTION: Edited by Annemie M.W.J. Schols and Labros S. Sidossis Source Type: research
HIGH cholesterol can set you on course to develop heart disease so it is vital to nip it in the bud. A particular grain has been shown to lower two types of bad cholesterol.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Cardiovascular diseases (CVDs) are the main cause of mortality worldwide. Risk factors of CVD can be classified into modifiable (smoking, hypertension, diabetes, hypercholesterolemia) through lifestyle changes or taking drug therapy and not modifiable (age, ethnicity, sex and family history). Elevated total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C) levels have a lead role in the development of coronary heart disease (CHD), while high levels of high-density lipoprotein-cholesterol (HDL-C) seem to have a protective role. The current treatment for dyslipidemia consists of lifestyle modification or drug...
Source: Journal of Cardiovascular Medicine - Category: Cardiology Tags: Review Source Type: research
Researchers here suggest that the processes of atherosclerosis, leading to the buildup of fatty deposits that narrow and weaken blood vessels, are cumulative over time. One of the risk factors is high blood cholesterol, and high cholesterol in youth is found to correlate with increased risk in later life, even if blood cholesterol has been restored to normal levels at that time. This is interesting, as the cause of atherosclerosis is less blood cholesterol per se and more the oxidized cholesterol that disrupts the function of macrophage cells responsible for cleaning up cholesterol in blood vessel walls. Those macrophages ...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Objective To investigate the association between non–high-density lipoprotein cholesterol/apolipoprotein A-I and monocyte/high-density lipoprotein cholesterol ratio and degree of coronary artery stenosis proven by coronary angiography. Methods A total of 1867 patients were enrolled into this study and analyzed retrospectively. Three hundred eighty-five non-coronary artery disease hospitalized patients were selected as control group, 1482 patients diagnosed as coronary artery disease were classified into three subgroups according to the tertiles of their SYNTAX score. We compared the level of non–high-densi...
Source: Coronary Artery Disease - Category: Cardiology Tags: Lipids and Inflammation Source Type: research
Conditions:   Rheumatic Heart Disease;   Valvular Disease Interventions:   Drug: Atorvastatin;   Drug: Placebo Sponsors:   University of Washington;   Manmohan Cardiothoracic Vascular and Transplant Center;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
By KEN TERRY (This is the eighth and final installment in a series of excerpts from Terry’s new book, Physician-Led Healthcare Reform: a New Approach to Medicare for All, published by the American Association for Physician Leadership.) Medical technologies include drugs, devices, tests, and procedures. Considered as a whole, these technologies are the key driver of growth in health costs, according to Georgetown University professor Gregg Bloche and his associates. Bloche, et al., view insurance coverage as the chief enabler of these technological innovations. In a 2017 Health Affairs Blog post, they sai...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Policy Ken Terry Source Type: blogs
Conditions:   Rheumatic Heart Disease;   Valvular Disease Interventions:   Drug: Atorvastatin;   Drug: Placebo Sponsors:   University of Washington;   Manmohan Cardiothoracic Vascular and Transplant Center;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: Our study provides a novel supramolecular nanomaterial to inhibit pathological progress of atherosclerosis through regulating cholesterol efflux and inflammation, which may contribute to the development of a promising nanomedicine for the treatment of atherosclerosis in the clinic.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
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