2-Substituted 2'-Deoxyinosine 5'-Triphosphates as Substrates for Polymerase Synthesis of Minor-Groove-Modified DNA and Effects on Restriction Endonuclease Cleavage

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02502B, PaperJan Matyasovsky, Michal Hocek Five 2-substituted 2'-deoxyinosine triphosphates (dRITP) were synthesized and tested as substrates in enzymatic synthesis of minor-groove base-modified DNA. Only 2-methyl and 2-vinyl derivatives proved to be good substrates for Therminator... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research