Acute changes in colonic PGE 2 levels as a biomarker of efficacy after treatment of the Pirc (F344/NTac-Apc   am1137 ) rat with celecoxib

ConclusionsAcute changes in colonic mucosa PGE2 provided a rapid means of predicting long-term chemopreventive effects from celecoxib, and might be useful for screening of new COX-2 inhibitor compounds.
Source: Inflammation Research - Category: Research Source Type: research