Breast Cancer Meeting'Is Going to Be Spectacular'Breast Cancer Meeting'Is Going to Be Spectacular '
The 2019 San Antonio Breast Cancer Symposium is chock-full of important research and presentations, said one of the meeting directors.Medscape Medical News
ConclusionsWomen whose treatment did not conform to NCCN guidelines were not associated with worse outcomes.
Authors: Dolatkhah M, Omidi Y Abstract The highly proliferating cancerous cells can form permissive accommodating milieu - the so-called tumor microenvironment (TME). During the initiation of solid tumors, hypoxia plays a key role in glycolysis, which can trigger the anomalous overexpression of several enzymes and transporters involved in the metabolism of glucose. Of these, carbonic anhydrases (CAs), especially CAIX, together with other molecular machinery involved in the production/trafficking of acidic byproducts, play key roles in the regulation of intracellular and extracellular pH. CAIX, along with other mole...
Conclusions Our findings can contribute to the development of breast cancer survivorship care plans by emphasizing posttreatment SM. Implications for Practice Future SM support intervention for BCSs after treatment should focus on training SM skills, enhancing the survivor-provider relationship, and building survivor self-confidence.
Conclusions Researchers need to consider these practical issues in future technology-based intervention research. Implications for Practice These issues need to be considered in future program/intervention development and implementation among racial/ethnic minority cancer survivors.
Conclusions Cancer experiences changed the women’s lives. Their coping varied. Fewer but selected supporters were preferred. Understanding and recognition from others for the women’s changed life situation was essential. Implications for Practice Healthcare professionals should prepare women for a changed life situation because of illness experiences and the adverse effects of treatments. The support and information offered must be adjusted to each woman’s individual needs, coping capacity, and life situation. Further clinical intervention studies are needed.
Conclusion Our finding supports the effectiveness of 1-month TRE in improving HL and all components of the International Classification of Functioning, Disability and Health status, except the activity component among breast cancer in Taiwan. Implications for Practice Clinicians could incorporate the TRE techniques in the rehabilitation sessions according to the healthcare, disease prevention, and health promotion domains to improve the clinical outcomes as well as change their health behaviors and attitudes of patients with breast cancer.
Background Chemotherapy leads to various symptoms and psychological distress, which contribute to a significant decrease in the quality of life of the patients. Objectives The aim of this study was to identify changes and interrelationships in the fatigue-depression-anxiety symptom cluster and quality of life during the cancer care trajectory in women with breast cancer. Methods Fifty women participated in the study and completed questionnaires at 3 different times: prechemotherapy, postchemotherapy, and 6 months after the completion of chemotherapy. The assessment tools were the Functional Assessment of Cancer The...
Background Women are at risk of mood disturbance during treatment for breast cancer. Objective The aims of this study were to identify classes of women experiencing similar trajectories of depressed mood and anxiety while receiving chemotherapy for breast cancer and to determine associated antecedents and outcomes. The specific aims were to (1) determine the distinct trajectory classes associated with severity of depressed mood and anxiety reported by women undergoing cycles 2 and 3 of chemotherapy for breast cancer, (2) determine if class membership is associated with various antecedent variables, and (3) determine i...
Permanent hair dye and chemical hair straightener use was linked to a higher risk of breast cancer in a new study from researchers at the National Institutes of Health.
CONCLUSIONS: Consequently, targeted therapies based on the interaction of PI3K inhibition with BRCA1 mutations or HR deficiency in TNBC may be a promising strategy for the treatment of patients with TNBC. PMID: 31804921 [PubMed - in process]