Teenager's memory was wiped OVERNIGHT due to a brain-swelling condition

Rafaela Domingos, now 17, of Ashford, Kent, didn't recognise her parents or even herself due to the condition encephalitis. She was placed in a coma to save her life.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Conditions:   Meningitis;   Encephalitis;   Abscess Brain Intervention:   Other: Pragmatic, multi-component package Sponsors:   University of Liverpool;   National Institute for Health Research, United Kingdom;   Christian Medical College, Vellore, India;   National Institute of Mental Health and Neuro Sciences, India;   Oswaldo Cruz Foundation;   Malawi-Liverpool-Wellcome Trust Clinical Research Programme;   University of Malawi College of Medicine;   University of Warw...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Vincent speaks with Félix Rey about his career and his work on solving structures of a variety of viruses and the insights learned about viral membrane fusion and antibody-mediated neutralization. Click arrow to play Download TWiV 577 (46 MB .mp3, 75 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology antibody neutralization cryo-EM dengue virus flavivirus fusion loop glycoprotein Semliki Forest virus tick borne encephalitis virus viral viral membrane fusion viruses X-ray crystallography zika virus Source Type: blogs
Publication date: Available online 6 December 2019Source: Antiviral ResearchAuthor(s): Andrew M. Skidmore, Robert S. Adcock, Colleen B. Jonsson, Jennifer E. Golden, Dong-Hoon ChungAbstractVenezuelan equine encephalitis virus (VEEV) is an alphavirus that is endemic to the Americas. VEEV outbreaks occur periodically and cause encephalitis in both humans and equids. There are currently no therapeutics or vaccines for treatment of VEEV in humans. Our group has previously reported on the development of a benzamidine VEEV inhibitor, ML336, which shows potent antiviral activity in both in vitro and in vivo models of infection. In...
Source: Antiviral Therapy - Category: Virology Source Type: research
We report a case of a young male admitted with H1N1 infection complicated by pneumomediastinum. He was treated successfully with oseltamivir, high-flow oxygen and prompt care in the intensive care unit. PMID: 31808456 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research
Authors: Goodfellow JA, Mackay GA Abstract Autoimmune encephalitis is emerging as an important and relatively common cause of encephalitis in the developed world. Crucially, early recognition and prompt initiation of a range of immunotherapies is likely to improve the outcomes of patients with autoimmune encephalitis, particularly for those with identifiable antibodies against neuronal cell surface proteins. There are a rapidly growing number of specific autoantibodies and associated syndromes, but many of these remain very rare. The majority of cases comprise anti-N-methyl-D-aspartate (NMDA) receptor encephalitis ...
Source: Journal of the Royal College of Physicians of Edinburgh - Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research
In this study we analysed the clinical profile of meningoencephalitis and its clinical outcome. METHODS: Fifty adults diagnosed with meningoencephalitis from July 2014 to July 2015 in a tertiary care hospital in South India were studied prospectively and their clinical presentation, aetiology and outcome were analysed. RESULTS: Among 50 patients, 33 (66%) were male; 39 (78%) were
Source: Journal of the Royal College of Physicians of Edinburgh - Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research
In conclusion, our in vitro and in vivo experimental findings show that P1 possesses antiviral activity against JEV infections, is safe to use, and has potential for further development as an antiviral treatment against JEV infections.
Source: Antiviral Therapy - Category: Virology Source Type: research
Source: Neurological Sciences - Category: Neurology Source Type: research
We describe the case of a 29-year-old male with NMDAR encephalitis and overlapping MOG antibody disease.
Source: Journal of Neuroimmunology - Category: Allergy & Immunology Authors: Tags: Short Communication Source Type: research
Infections with commonly occurring Australian arthropod-borne arboviruses such as Ross River virus (RRV) and Barmah Forest virus (BFV) are diagnosed routinely by pathology laboratories in Australia. Others, such as Murray Valley encephalitis (MVEV) and Kunjin (KUNV) virus infections may be diagnosed by specialist reference laboratories. Although Alfuy (ALFV), Edge Hill (EHV), Kokobera (KOKV), Sindbis (SINV), and Stratford (STRV) viruses are known to infect humans in Australia, all are considered ‘neglected.’ The aetiologies of approximately half of all cases of undifferentiated febrile illnesses (UFI) in Austra...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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