Exendin-based glucagon-like peptide-1 receptor agonists and anaphylactic reactions: a pharmacovigilance analysis

Publication date: Available online 2 December 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Richeek Pradhan, François Montastruc, Vanessa Rousseau, Elisabetta Patorno, Laurent Azoulay
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research

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CONCLUSIONS: Teachers of the study were concerned about not knowing what to do in an emergency event in a schoolchild with chronic illness. Although some had received information about the medication to be administered, they were not sure if they would be able to do so. The training and self-confidence of teachers should be improved in order to cope with possible critical situations in schoolchildren with chronic diseases. PMID: 32205056 [PubMed - as supplied by publisher]
Source: Anales de Pediatria - Category: Pediatrics Authors: Tags: An Pediatr (Barc) Source Type: research
By ANDY MYCHKOVSKY In order to celebrate the next decade (although the internet is confused whether its actually the end of the decade…), we’re taking a step back and listing our picks for the 9 most influential healthcare companies of the 2010s. If your company is left off, there’s always next decade… But honestly, we tried our best to compile a unique listing that spanned the gamut of redefining healthcare for a variety of good and bad reasons. Bon appétit! 1. Epic Systems Corporation The center of the U.S. electronic medical record (EMR) universe resides in Verona, Wisconsin. Po...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Tech Health Technology Start-Ups Andy Mychkovsky Healthcare Pizza Innovation Startups Source Type: blogs
Abstract Atrial fibrillation is the most common cardiac arrhythmia in western society affecting more than 35 million individuals worldwide annually. It is a common postoperative complication and may also occur spontaneously during general and local anesthesia administration. Aging, diabetes mellitus, hypertension, and cardiovascular diseases including cardiomyopathies, congenital cardiac anomalies, heart failure, myocardial ischemia, pericarditis, previous cardiac surgery, vascular disease, and valvular heart disease are some correlated factors. Beyond age, increased incidence of atrial fibrillation has been corre...
Source: Annals of Cardiac Anaesthesia - Category: Anesthesiology Authors: Tags: Ann Card Anaesth Source Type: research
We report a case of angioedema and anaphylaxis due to Dulaglutide.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Adverse Drug Reactions, Insect Reactions, Anaphylaxis Source Type: research
ConclusionsChildren with hospital records of chronic conditions, particularly epilepsy and asthma, might benefit from school-based care plans that integrate their physical and mental health support needs.
Source: Journal of Pediatric Psychology - Category: Pediatrics Source Type: research
Márta L. Debreczeni1, Zsuzsanna Németh1, Erika Kajdácsi1, Endre Schwaner1, Veronika Makó2, András Masszi1, Zoltán Doleschall3, János Rigó4, Fruzsina R. Walter5, Mária A. Deli5, Gábor Pál6, József Dobó7, Péter Gál7 and László Cervenak1* 1Research Laboratory, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary 2MTA-SE Research Group of Immunology and Hematology, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary 3Department of Pathogenetics, National I...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
We describe one such approach, albumin binding, and explain how it was applied in the development of the human GLP-1 analog liraglutide once daily and, subsequently, semaglutide once weekly. The pharmacology of these two long-acting GLP-1 analogs, in terms of improving glycemic control, reducing body weight and decreasing cardiovascular (CV) risk, is also reviewed, together with some novel biology. In addition, we describe the importance of accurate target (GLP-1 receptor) tissue expression analysis. Now an established class of agents, GLP-1-based therapies represent a significant advance in the treatment of T2D. All curr...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Superparamagnetic iron oxide nanoparticles (SPIONs) are increasingly utilized alternatives to gadolinium-based Magnetic Resonance Imaging (MRI) contrast agents in the diagnosis of osteomyelitis in diabetic patients with renal failure [1]. Ferumoxytol is approved by the United States Food and Drug Administration (FDA), the European Medicines Agency, for intravenous (IV) use for iron replacement therapy [1-3]. Ferumoxytol is composed of an iron-carbohydrate complex that minimizes dissociation and appearance of free iron into the serum.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
This article is protected by copyright. All rights reserved. PMID: 30242842 [PubMed - as supplied by publisher]
Source: European Journal of Immunology - Category: Allergy & Immunology Authors: Tags: Eur J Immunol Source Type: research
CONCLUSION: The majority of thrombosed accesses can be successfully treated, maintaining its long-term patency. The need of repeated intervention is frequent. PMID: 30207374 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
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