Coexistence of unusual and distinctive initial manifestations of severe systemic lupus erythematosus: A child 's case, presenting as adrenal insufficiency associated with autoimmune polyglandular syndrome

This report describes the overlap of unexpected, unusual, and severe clinical findings in an infant with APS with a comorbidity of SLE, where the involvement of multiple endocrine organs coexists with multiple serious clinical manifestations from the beginning.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research

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Publication date: Available online 21 January 2020Source: Enzyme and Microbial TechnologyAuthor(s): Hyunjun Choe, Minsun Cha, Jon D. StewartAbstractSerine palmitoyltransferase (SPTase), the first enzyme of the sphingolipid biosynthesis pathway, produces 3-ketodihydrosphingosine by a Claisen-like condensation / decarboxylation reaction of L-Ser and palmitoyl-CoA (n-C16-CoA). Previous structural analysis of Sphingomonas paucimobilis SPTase (SpSPTase) revealed a dynamic active site loop (RPPATP; amino acids 378 - 383) in which R378 (underlined) forms a salt bridge with the carboxylic acid group of the PLP : L-Ser external ald...
Source: Enzyme and Microbial Technology - Category: Biotechnology Source Type: research
Publication date: February 2020Source: Journal of Catalysis, Volume 382Author(s): Trenton J. Wilke, Mark A. BarteauAbstractTurnover frequencies for methanol dehydration and oxidation with supported polyoxometalate catalysts exhibit a strong dependence on the extent of proton exchange with other cations. Harned’s rule, which is typically used to describe the thermodynamic activity of acid and salt solutions, was used to model thermodynamic activity coefficients for cation-exchanged, supported polyoxometalates. The resulting activity coefficients described the dehydration and oxidation turnover frequencies of supported...
Source: Journal of Catalysis - Category: Chemistry Source Type: research
In this study, polymorphic thin films of MnS2, γ-MnS, and α-MnS were prepared... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - Category: Chemistry Authors: Source Type: research
This article explains how Al Qaeda in the Islamic Maghreb (AQIM)-trained Nigerian militants split from Boko Haram and formed a new group called Ansaru in 2011 after consulting with AQIM. Ansaru leaders, however, reintegrated with Boko Haram and transferred...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news
[Premium Times] At least 16 people have so far died in a fresh outbreak of Lassa Fever in Ondo State, the state government has confirmed.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
ConclusionsIt was concluded that physiotherapists had sufficient knowledge about epilepsy and were using current skills/physical activity in the rehabilitation of children with epileptic seizures.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: April 2020Source: Materials Science in Semiconductor Processing, Volume 109Author(s): L. Hill-Pastor, T. Díaz-Becerril, R. Romano-Trujillo, M. Galván-Arellano, R. Peña-SierraAbstractThe effects of sodium chloride (NaCl) or sodium hydroxide (NaOH) used to control the p-type conductivity of cuprous oxide Cu2O thin films by reactive thermal annealing (ReTA) at 550 °C in low oxygen content applied to NaX/Cu2O (X = Cl or OH) bilayers were studied. NaX nanolayers were deposited by dipping the Cu2O films in their saturated solutions. It has been reported that annealing Cu2...
Source: Materials Science in Semiconductor Processing - Category: Materials Science Source Type: research
Publication date: May 2020Source: Materials Science and Engineering: C, Volume 110Author(s): Pengzhao Lv, Lianjie Zhu, Yanmiao Yu, Wenwen Wang, Guokai Liu, Hongguang LuAbstractA series of Cu nanoparticles (NPs) have been prepared by a facile hydrothermal method at 180 °C using different concentrations of NaOH solutions and characterized by XRD, SEM, TEM and FT-IR spectra. Their antibacterial activities were assessed by means of Gram-positive S. aureus and Gram-negative E. coli bacteria, where various dosages (3, 5, 7, 10 mg) of the antibacterial agents were applied, and compared with that of the commercial Cu...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Conclusions: This analysis highlights the importance of an early diagnosis and initiation of therapeutic management when AI is suspected. In line, signs and symptoms related to autoimmune diseases in patients with AI should be reviewed crtitically.
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
This article will review the causes of bleeding in aPL-positive patients as well as the management strategies.
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research
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