Mosquitoes bring ‘mystery illness’ to the mountain villages of Nepal

Rising temperatures linked to outbreaks of dengue fever high in the Kathmandu Valley, experts say•Global heating behind record number of cases of the diseaseLilawati Awasthi is used to the risks that come from living in a remote mountainous district in the far west of Nepal. Floods, landslides and treacherous roads are a part of daily life. But this year she faced a new hazard: mosquitoes carrying a mystery illness.When she began to feel sick in September she was not overly concerned at first. “I thought it was a simple fever, but it wouldn’t go away,” says the 50-year-old. “We went to the hospital and it turned out I was suffering from dengue.”Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Nepal Infectious diseases Climate change Environment Global development South and Central Asia Microbiology Science World news Source Type: news

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by Rattanam AhbiRami, Wan Fatma Zuharah The massive flood in Malaysia’s east coast in December 2014 has placed Kelantan in a possible dengue outbreak risk. At this point, community awareness is essential in preventing disease spread. However, no data on knowledge, attitude, and practice (KAP) of dengue in Kelantan have existed in rele vance to flood disaster, although such information is necessary for the vector control programs. The purpose of this study is to assess the KAP regarding dengue among school children from flooded and unflooded areas and to evaluate the effectiveness of the dengue health education progr...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
ConclusionCHIKV is an important cause of illness amongst patients presenting with acute febrile illness in Sindh region of Pakistan. Arthralgia and encephalitis at time of presentation among patients with dengue-like illness should prompt suspicion of CHIKV infection, and laboratory confirmation must be sought.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Abstract Dengue is the most important mosquito-borne viral infection in Sri Lanka causing an enormous social and economic burden in the country. In the absence of therapeutic drugs and the developed vaccines are under investigation, vector control is the best strategy to reduce the disease transmission. Therefore, the development of novel tools to control dengue vector mosquitoes has become the need of the hour. Novaluron is a recently developed Insect Growth Regulator (IGR) which inhibits chitin synthesis in immature stages of insects. The aim of the study was to identify the efficacy of a simple and cost-effecti...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
It might seem like the world has slowed down to a crawl amid the coronavirus (COVID-19) pandemic, but there are still some companies out there raising money. E25Bio is one of those companies – bringing in $2 million in funding from Khosla Ventures. The Cambridge, MA-based company develops technology for rapid diagnosis of dangerous infectious diseases such as dengue, zika, and now COVID-19. Financing will go toward research and development, clinical studies, and scaling the company’s launch for diagnostic tests upon receiving Emergency Use Authorization approval. E25Bio’...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
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Source: NaturalNews.com - Category: Consumer Health News Source Type: news
This study investigated the circulation of DENV serotypes, viremia levels, immunological status, and cytokine levels, with disease severities among children infected in 2017 in Ho Chi Minh City, Southern Vietnam. Acute and convalescent serum samples were collected from clinically diagnosed dengue children. They were confirmed to have DENV infection by NS1 antigen, IgM and IgG ELISAs, virus isolation, and conventional and real-time RT-PCR. Measurement of 10 cytokine levels was performed in the serum samples. All the children were dengue IgM positive; 28% and 72% of them had primary and secondary DENV infections, respectivel...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
On 12 February 2020, the European Centre for Disease Prevention and Control (ECDC) reported an increase in the number of cases of dengue infection in French Guiana, Guadeloupe, Martinique, and Saint-Martin. In January 2020, health authorities in the region declared a dengue epidemic in Guadeloupe and Saint-Martin and indicated that Martinique is also at-risk of an epidemic. Dengue epidemics in these territories usually occur when there is a shift in the predominant circulating DENV serotype, and non-immune populations (e.g., tourists, new immigrants, or people not previously exposed to the circulating serotypes) are expose...
Source: WHO Disease Outbreaks - Category: Infectious Diseases Tags: news Source Type: news
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Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
In this study, the cytokine profile was suggestive of a T-helper 2 response. Most patients had secondary infection, and the levels of viremia were higher in patients with plasma leakage than those without plasma leakage. In addition, we observed that bleeding and hepatitis were associated with significantly higher levels of IL-8 during the early phases of infection. Furthermore, IL-6 levels in the early phase of infection were also elevated in bleeding patients with plasma leakage. These results suggest that IL-6 and IL-8 may act in synergy to cause bleeding in patients with plasma leakage. PMID: 32124729 [PubMed - as...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
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