Childhood Adversity Linked to Borderline Personality Disorder

MONDAY, Dec. 2, 2019 -- Exposure to childhood adversity is associated with borderline personality disorder (BPD), according to a review recently published in Acta Psychiatrica Scandinavica. Carly Porter, Ph.D., from the University of Manchester in...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Conclusion: Major limitations of the reviewed studies were short trial duration, small sample sizes, and the lack of control groups. Defining the potential role of DUL in the treatment of psychiatric disorders other than major depressive disorder and generalized anxiety disorder needs further randomized, placebo-controlled studies.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Gyöngyi Kökönyei1,2,3*, Natália Kocsel1,2,3,4, Orsolya Király1, Mark D. Griffiths5, Attila Galambos1,2,4, Anna Magi1,4, Borbála Paksi6 and Zsolt Demetrovics11 Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary2SE-NAP2 Genetic Brain Imaging Migraine Research Group, Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary3Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest, Hungary4Doctoral School of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary5Psychology Department, Not...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
In this study, using multiple linear regression analysis, we found that decreased emotion coping appraisal of resilience in young adults was explained by an increased tendency to update beliefs about cue–outcome associative probability in a volatile environment and the increase in the parental verbal abuse experienced in early childhood. The total scores of resilience appraisals were also explained in the same manner (see Supplementary Tables 4 and 7). In addition, we did not find any effect of gender on the results both with whole subject (Figure 4) and in the gender-matched subgroup (see Supplementary Figure 3).Not...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
This study provides support for the notion that non-judgmental attention to the present moment facilitates the integration of regions in neural networks that are related to cognition, attention, and sensation. Introduction Originating in Buddhist traditions, mindfulness training has made its way into Western culture as a method to reduce stress, enhance emotional regulation, and reduce symptoms in a variety of mental health disorders (Teasdale et al., 1995; Farb et al., 2012; Cavanagh et al., 2013; Tabak et al., 2015). Indeed, mindfulness has been shown to reduce symptoms of depression (Chiesa et al., 2015), bipol...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Conclusion It is clear that clinically, there is still much to be learnt about alexithymia and its relationship with a range of related phenomena. Firstly, is alexithymia a continuous and stable trait independent of psychological or somatic symptomology that is developed during childhood? Or is it instead a reactive state induced by trauma and distress at any age, which serves to defend against intense and upsetting emotions? This impacts on treatment options. For example, should we be focussing on early childhood interventions which target the child's emotional environment and parenting to encourage emotional exp...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Alexandra Neyazi1†, Vanessa Buchholz1†, Alexandra Burkert1, Thomas Hillemacher1,2, Martina de Zwaan3, Wolfgang Herzog4, Kirsten Jahn1, Katrin Giel5, Stephan Herpertz6, Christian A. Buchholz1, Andreas Dinkel7, Markus Burgmer8, Almut Zeeck9, Stefan Bleich1, Stephan Zipfel5† and Helge Frieling1*† 1Molecular Neuroscience Laboratory, Department of Psychiatry, Social Psychiatry, and Psychotherapy, Hannover Medical School (MHH), Hannover, Germany 2Department of Psychiatry and Psychotherapy, Paracelsus Medizinische Privatuniversität Nürnberg, Nuremberg, Germany 3Department of Psychos...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
This study, therefore, compares reappraisal of negative, positive, neutral, and alcohol-related images at a behavioral and neural level between ADPs and healthy controls (HCs).Thirty-nine ADPs and 39 age-, gender-, and education-matched HCs performed an emotion reappraisal task during functional magnetic resonance imaging (fMRI), and craving was measured before and after the reappraisal task. During the emotion reappraisal task, participants were instructed to either attend or reappraise positive, negative, neutral, or alcohol-related images, and to indicate their experienced emotion on a visual analogue scale (VAS).Both A...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
CONCLUSIONS: The negative self-views that BPD have, may obstruct critically examining negative feedback, resulting in lower mood. Moreover, where HC focus on the positive feedback (based on TPJ activation), BPD seem to focus more on negative feedback, potentially maintaining negative self-views. Better balanced self-views may make BPD better equipped to deal with potential negative feedback and more open to positive interactions. PMID: 30867073 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
AbstractRecent resting-state functional connectivity studies have shown significant group differences in several networks between patients suffering from borderline personality disorder (BPD) and healthy controls. However, reliable and consistent findings have not been reported yet. Several methodological factors might be responsible for the discrepant findings, including the heterogeneity of patient samples in terms of symptom severity. In the current study, we combined investigations of the whole-brain resting-state functional connectivity patterns of BPD patients with seed-based connectivity measures and then computed t...
Source: Brain Imaging and Behavior - Category: Neurology Source Type: research
Abstract Difficulty in anger control and anger-related aggressive outbursts against others are frequently reported by patients with borderline personality disorder (BPD). Although male sex is a known predictor for aggression, hardly any study has addressed the neural correlates of deficient anger control in male patients with BPD. Building on previous reports in female BPD, we investigated the involvement of lateral antero- and dorsal prefrontal cortex in the control of fast emotional actions and its relation to self-reported tendencies to act out anger. 15 medication-free male patients with BPD and 25 age- and in...
Source: Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Neuropharmacology Source Type: research
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