Drinking kudingcha can help lower your risk of colitis
(Natural News) Researchers from the Chongqing University of Education in China looked at the potential of functional foods – in particular, kudingcha or kuding tea – to treat ulcerative colitis. They found that kuding tea could help treat and prevent ulcerative colitis without side effects. Kuding tea is a bitter-tasting tea which is popular in China. It is used to quench thirst,...
Authors: Liu Z, Xie W, Li M, Liu J, Liang X, Li T Abstract Polaprezinc (PZ), a chelate of zinc and L-carnosine, has been widely used in the treatment of gastric ulcers since 1994. In recent years, researchers have found PZ to have a beneficial effect on various experimentally induced models of colitis in mice. In the present study, 6% dextran sodium sulfate (DSS) was used to induce a model of ulcerative colitis (UC) in Institute of Cancer Research mice. The therapeutic effect and mechanism of PZ action in a model of UC was studied in order to provide an experimental basis for the clinical application of PZ in UC tr...
ConclusionsApheresis was well tolerated as maintenance therapy for UC although the cumulative clinical remission rate at 12 months was comparable between the apheresis and control groups.
The efficacy of antibody-based therapeutics depends on their pharmacokinetics. The pharmacokinetic and exposure response profiles of ustekinumab, a monoclonal antibody against interleukin 12/interleukin 23, are known in patients with Crohn ’s disease, yet there are few data from patients with ulcerative colitis. We characterized ustekinumab’s pharmacokinetics, exposure response, and optimal serum concentrations in patients with ulcerative colitis.
Abstract The skin is the largest human organ, comprising the epidermis that is composed of epithelial tissue, the dermis composed of connective tissue, and the innermost subcutaneous tissue. Generally, skin conditions are due to aging and the influence of the external environment, but empirically patients with gastrointestinal diseases are more prone to pruritus and inflammation caused by dry skin. A decrease in the skin barrier function, involving immunocompetent mast cells and oxidative stress, was noted in indomethacin-induced small intestine inflammation, dextran sodium sulfate (DSS)-induced ulcerative colitis...
Clonal hematopoiesis of indeterminate potential (CHIP) is a pre-malignant condition associated with expansion of blood cell populations driven by age-dependent acquisition of somatic mutations in hematopoietic stem cells (HSCs)[1-7]. Although CHIP mutations are typically present at low variant allele fraction (VAF), they are cancer-drivers and frequently involve genes mutated in myeloid malignancies [1-3, 8]. Despite the overall prevalence of CHIP, few of these individuals progress to hematopoietic malignancy [1, 2, 5, 7, 8].
Which endoscopic procedure best identifies neoplasia in patients with ulcerative colitis or Crohn disease?Alimentary Pharmacology &Therapeutics
(University of California - Riverside) A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.
CONCLUSIONS: At adolescence, both Crohn's disease and ulcerative colitis are associated with multiple comorbidities, not limited to autoimmune disorders. PMID: 31801156 [PubMed - as supplied by publisher]
Conclusion: Our results show both genotypic and phenotypic associations of IL-10 SNPs with IBD but not with the other immune-related SNPs studied in this Mexican cohort.
Conclusion For patients with a low faecal calprotectin level, sigmoidoscopy might be sufficient to assess mucosal healing.