Doctors bring a dead heart 'back to life' for groundbreaking transplant
An estimated 4,000 people are waiting for heart transplants, but the donated organs only last six hours outside a body. Duke University's method, could extend that timeline and save lives.
The Organ Care System, or Heart in a Box, gives surgeons about 12 hours to get the heart to the recipient, double the amount of time in a traditional transplant
CONCLUSION: Implementation of the LVAD Emergency Line has improved communication between patients in the outpatient setting. This increased patient safety by allowing patients to speak to LVAD-trained first responders and VAD coordinator personnel immediately without ever being put on hold. This communication process can be applied to other clinical programs. PMID: 31789980 [PubMed - in process]
For the first time in the U.S., doctors have brought a heart back to life and successfully transplanted it into another person. They used a special device to revive the heart of a 26-year-old donor who died of cardiac arrest on Sunday. The doctors then transported the beating heart from Ohio to Duke University Hospital in North Carolina where surgeons transplanted it into a military veteran. Dr. Tara Narula joins "CBS This Morning" to discuss the Organ Care System or Heart-in-a-Box device.
Doctors at Duke University Medical Center performed the first donation after circulatory death heart transplant on an adult in the United States on December 1.
Years of research of candidates for heart transplantation led to crafting the recent donor heart allocation system in the United States, implemented in October 2018, which was designed to allow more equitable organ allocation of patients awaiting heart transplantation, to reduce mortality in the waiting list and to preserve excellent outcomes post-heart transplant. In this issue of the Journal, Cogswell and colleagues examine key changes in patient characteristics and post transplant outcomes in the period of 3 years before and 5.4 months after the change of the US allocation algorithm.
This study sought to investigate the optimal perfusion strategy for pediatric DCD hearts by using a juvenile porcine model comparing pressure- vs. flow-targeted strategy.
Between 16 and 51% of chronic thromboembolic pulmonary hypertension (CTEPH) patients will have residual pulmonary hypertension (PH) after pulmonary endarterectomy (PEA). Whether residual PH is related to remaining (sub-)segmental macrovascular lesions or to microvascular disease is unknown. New imaging techniques can provide detailed information about (sub-)segmental pulmonary arteries and parenchymal perfusion. The aim of this study was to describe the prevalence after PEA of remaining (sub-)segmental vascular lesions on ECG-gated CT pulmonary angiography (CTPA) and parenchymal hypoperfusion on MR and to relate these imag...
AbstractWhereas bicaval technique is an effective surgical method, standard bicaval technique for younger age and donor/recipient caval mismatch was reported to have a risk of superior vena caval obstruction. Between 2016 and 2019, three patients with dilated cardiomyopathy aged 10 years or younger underwent orthotropic heart transplantation with modified bicaval technique at our institute. Donor/recipient body weight and height ratios were 2.36, 0.77, and 2.61 and 1.37, 0.94, and 1.51, respectively. All patients were preoperatively supported by a left ventricular assist dev ice: Excor Pediatric in two patients and J...
ConclusionA high suspicion level for TB, the early diagnosis and the prompt initiation of therapy could increase the survival rates among SOT patients. Overall, renal and lung TRs appear to have a higher predisposition for acquiring TB than other type of recipients. Monitoring of the high-risk recipients, prompt diagnosis, and appropriate treatment are required to manage TB infection among TRs especially in endemic areas.
AbstractPurpose of ReviewWhile morbidity and mortality remain high for amyloid cardiomyopathy (AC), increased awareness, earlier diagnosis, and advances in treatment have improved patient outcomes. This review will discuss the pathophysiology, contemporary diagnostic strategies, and novel and investigational therapeutic strategies for light-chain (AL) and transthyretin (ATTR) AC.Recent FindingsDiagnostic strategies for AC now include cardiac magnetic resonance imaging and bone scintigraphy. Proteosome inhibitor therapy is now front-line therapy for AL AC followed by autologous stem cell transplantation. Emerging disease-mo...