Insulin Resistance in Type 1 Diabetes Mellitus and Its Association with Patient ’s Micro- and Macrovascular Complications, Sex Hormones, and Other Clinical Data

AbstractIntroductionThe main objective of this research was to evaluate the association of insulin resistance (IR) with micro- and macrovascular complications, sex hormones, and other clinical data.MethodsCross-sectional study of patients older than 18  years old with type 1 diabetes mellitus (T1DM) was performed. Participants filled in questionnaires about T1D, disease duration, smoking, glycemic control, chronic diabetes complications, and hypertension status. Data about chronic diabetic complications (neuropathy, retinopathy, and nephropathy) were collected from medical records. History of major cardiovascular events such as angina, myocardial infarction, and stroke were collected from medical records also. Laboratory tests including creatinine, cholesterol levels, testosterone (T), sex hormone-binding globulin (SHBG), estradiol levels, and albumin in 24-h urine sample were performed. IR was calculated using the following formula: estimated glucose disposal rate (eGDR) = 24.31 − [12.22 × waist-to-hip ratio (WHR)] − [3.29 ×  hypertension status (defined as 0 = no, 1 = yes)] − [0.57 × gl ycated hemoglobin (HbA1c)]. The data was considered statistically significant atp 
Source: Diabetes Therapy - Category: Endocrinology Source Type: research

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Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
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Source: Journal of Sports Medicine and Physical Fitness - Category: Sports Medicine Tags: J Sports Med Phys Fitness Source Type: research
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Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
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Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Crescendo transient ischemic attacks should be treated by carotid endarterectomy within two days – but with increased perioperative stroke risk Source Type: research
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Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Open-cell stents used for carotid artery stenting are less likely to develop recurrent stenosis than closed-cell stents Source Type: research
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Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Review article Source Type: research
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Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Invited commentary Source Type: research
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Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Invited commentary Source Type: research
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Source: Open Respiratory Medicine Journal - Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research
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