Pregnancy in Women with Complex Congenital Heart Disease. A Constant Challenge

Abstract Background: The improvement in surgical techniques has contributed to an increasing number of childbearing women with complex congenital heart disease (CCC). However, adequate counseling about pregnancy in this situation is uncertain, due to a wide variety of residual cardiac lesions. Objectives: To evaluate fetal and maternal outcomes in pregnant women with CCC and to analyze the predictive variables of prognosis. Methods: During 10 years we followed 435 consecutive pregnancies in patients (pts) with congenital heart disease. Among of them, we selected 42 pregnancies in 40 (mean age of 25.5 ± 4.5 years) pts with CCC, who had been advised against pregnancy. The distribution of underlying cardiac lesions were: D-Transposition of the great arteries, pulmonary atresia, tricuspid atresia, single ventricle, double-outlet ventricle and truncus arteriosus. The surgical procedures performed be fore gestation were: Fontan, Jatene, Rastelli, Senning, Mustard and other surgical techniques, including Blalock, Taussing, and Glenn. Eight (20,0%) pts did not have previous surgery. Nineteen 19 (47.5%) pts had hypoxemia. The clinical follow-up protocol included oxygen saturation recording, hemoglo bin and hematocrit values; medication adjustment to pregnancy, anticoagulation use, when necessary, and hospitalization from 28 weeks, in severe cases. The statistical significance level considered was p
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research

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Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Diabetes MMWR Morbidity & Mortality Weekly Report Pregnancy COVID-19 Coronavirus Disease 2019 Source Type: news
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Conditions:   Pregnancy Complications;   Pregnancy, High Risk;   Pregnancy Induced Hypertension;   Newborn Morbidity;   Fetal Growth Retardation;   Fetus Disorder;   Weight Gain, Maternal;   Maternal-Fetal Relations Interventions:   Other: Exercise program;   Other: Healthy lifestyle advise Sponsors:   Universidad Politecnica de Madrid;   Hospital Severo Ochoa;   Puerta de Hierro University Hospital;   Hospital Vall ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   The Relationship Between Oral Vitamin A Administration and the Incidence of BPD in Preterm Infants Born Before Week 29 of Pregnancy Intervention:   Dietary Supplement: Oral Vitamin A Sponsor:   Sheba Medical Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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