Association of dystrophic epidermolysis bullosa and neuroblastoma in a newborn
The term epidermolysis bullosa (EB) comprises a number of rare and genetically heterogenous disorders characterized by structural skin fragility that results in recurrent blister formation.1 Dystrophic epidermolysis bullosa (DEB) is a subtype of EB that is caused by mutations in the COLA1 gene encoding type VII collagen; it is characterized by blister formation in the dermis, directly beneath the epidermis, and sometimes in the mucous membranes.2 The reported incidence of DEB is 26.4 new cases per 1,000,000 live births.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Emilia Parodi, Elisa Tirtei, Maurizio Bianchi, Mario Frigerio, Isabella Morra, Paola Coppo Tags: Short Communication Source Type: research
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