Adiposity, depression and anxiety: interrelationship and possible mediators

CONCLUSIONS Depression, but not generalized anxiety disorder, is associated with adiposity in both directions, with a stronger evidence for the direction obesity-depression. Inflammation explains part of the effect of major depressive disorder on obesity but not the other way around. Further research should explore other mechanisms that could be involved in the association between obesity and depression.
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research

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Conclusions: Insomnia symptoms and obesity were related to overall aggressive behavior in PWE independent of depressive symptoms. The individual subscales of the AQ were correlated differently with the various factors including male sex, obesity, depressive symptoms, anxiety, insomnia symptoms, epilepsy severity, polytherapy, and the use of perampanel.
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 10 August 2019Source: Obesity Research &Clinical PracticeAuthor(s): Sanjeev Sockalingam, Samantha E. Leung, Raed Hawa, Susan Wnuk, Sagar V. Parikh, Timothy Jackson, Stephanie E. CassinAbstractObjectiveAlthough bariatric surgery is a durable treatment for patients with severe obesity, it does not directly address behavioural and psychological factors that potentially contribute to weight regain post-surgery. Psychological interventions, such as cognitive behavioural therapy (CBT), can be challenging to access due to physical limitations and practical barriers. Telephone-based CBT (Tele...
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
CONCLUSIONS: Adolescents consuming soft drinks ≥7 times/week, or >25 g sugar/d from soft drinks, had significantly higher levels of anxiety and depression. Dietary suggestion is needed to prevent anxiety and depression in adolescents. PMID: 31097051 [PubMed - as supplied by publisher]
Source: Public Health Nutrition - Category: International Medicine & Public Health Authors: Tags: Public Health Nutr Source Type: research
We reported DEGs with a nominal p-value of 0.8. The network construction was created using blockwiseModules function for consideration of computer efficiency. The module detection criteria were as follows: minimum module size of 50, deepsplit of 4, and merge threshold of 0.25. The merged modules were then summarized with module eigengene (ME) correlations>0.75. MEs were defined by their first principal component and were labeled with different colors as module names in the Results section. After the modules were generated, we conducted different enrichment analysis to explore the functional interpretation of genes withi...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
CONCLUSION: The experience of multiple mental disorders over the lifetime is extremely common, and associated with increased risk of mortality, most notably among men. Clinicians should be aware of the importance of considering contemporaneous symptoms of multiple psychiatric conditions. PMID: 30712520 [PubMed - as supplied by publisher]
Source: Epidemiology and Psychiatric Sciences - Category: Psychiatry Tags: Epidemiol Psychiatr Sci Source Type: research
CONCLUSIONS: Long-term associations of childhood ADHD with adverse physical health and socioeconomic outcomes underscore the need for early intervention. Young adult ADHD showed stronger associations with poorer mental health, substance misuse and psychosocial outcomes, emphasising the importance of identifying and treating adults with ADHD. The Study in Context: Neurofeedback or medication to treat ADHD? What are cognitive abilities and how to boost them? Rates of ADHD diagnosis and medication treatment continue to increase substantially
Source: SharpBrains - Category: Neuroscience Authors: Tags: Attention and ADD/ADHD Education & Lifelong Learning Health & Wellness ADHD symptopms attention deficit hyperactivity disorder Genetics mental health problems psychiatry Source Type: blogs
Addiction is an incredibly lonely disease. However, we typically associate addicts with two extremes when it comes to sociability. On the one hand we imagine the stereotypical “life of the party” who abuses substances to become sociable, friendly, and functional, or we have the depressive addict who takes substances alone, substituting healthy interpersonal relationships for chemicals. The truth is that most addicts may fall somewhere along this spectrum, but they all experience extreme feelings of isolation. As anyone who has suffered from addiction can vouch for, having a crippling reliance on substances can...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction Alcoholism Communication Family Friends Recovery Substance Abuse Treatment Loneliness self medicating Social Isolation Social Withdrawal Source Type: blogs
Conclusion: Adolescents with PCOS experience significantly more emotional distress compared to adolescents without PCOS. This emotional distress may be related, at least in part, to certain clinical features of PCOS including obesity and hirsutism. PCOS in adolescents should be assessed not only for the gynecological and metabolic aspects but also for the emotional aspects of the disease. PMID: 29914248 [PubMed]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
CONCLUSIONS: Illness perception and cardiac anxiety in patients with CVD were associated with anxiety and depression. Regression analysis showed that illness perception accounts for a significant proportion of the variance in both anxiety and depression for males, but not for females. Gender-specific interrelations between perceptions of CVD and indices of mental health have an implication for interventions to maximize the effect of therapy with these patients. LEVEL OF EVIDENCE: Level V, Descriptive study. PMID: 29726000 [PubMed - as supplied by publisher]
Source: Eating and weight disorders : EWD - Category: Eating Disorders & Weight Management Authors: Tags: Eat Weight Disord Source Type: research
We describe the effects of LDX (50mg and 70mg) on the Sheehan Disability Scale (SDS; exploratory endpoint) from both studies. Design: The SDS was assessed at baseline, Week 6, and Week 12/early termination. Analyses included mixed-effects models for repeated measures for the examination of SDS total and domain score changes and a generalized estimating equation model to assess dichotomized remission status (remission [total score ?6] versus nonremission [total score>6]). Results: Least squares (95% confidence interval [CI]) mean treatment differences for SDS total score change from baseline at Week 12 were -2.80 (-3.98,...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Drug Development Original Research binge eating disorder disability functionality lisdexamfetamine dimesylate Sheehan Disability Scale Source Type: research
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