Feeding problems and gastrointestinal diseases in Down syndrome.

This study lists the various anomalies on the basis of 504 references selected from a PubMed search in October 2018. RESULTS: The anomalies are grouped into three categories: anatomical anomalies: duodenal atresia and stenosis (3.9%), duodenal web and annular pancreas; aberrant right subclavian artery (12% of children with DS with cardiac anomaly); Hirschsprung's disease (2.76%); anorectal malformation (1.16%); congenital vascular malformations of the liver; orofacial cleft, bifid uvula (4.63%), and submucous orofacial cleft; esophageal atresia (0.5-0.9%); pyloric stenosis (0.3%); diaphragmatic hernia; malrotation of small intestine or duodenum inversum; omphalocele, gastroschisis or anomalies of the median line, anomalies of the umbilical vein; biological, immunological, and infectious anomalies: neonatal cholestasis (3.9%); neonatal hepatic fibrosis; Helicobacter pylori infection (75.8% in institutionalized children with DS, between 29.2 and 19.5% in non-institutionalized); non-alcoholic fatty liver disease (NAFLD; 82% in obese and 45% in non-obese); biliary lithiasis (6.9% under 3 years); celiac disease (6.,6%); geographical tongue (4%); hepatitis B virus sensitivity; autoimmune hepatitis and cholangitis; Crohn's disease, inflammatory bowel disease (IBD); pancreatitis; vitamin D deficiency (45.2% in Italy); functional disorders: suction, swallowing and chewing disorders (13 of 19 children with DS under 4 years); gastroesophageal reflux (47% in children with sleep apne...
Source: Archives de Pediatrie - Category: Pediatrics Authors: Tags: Arch Pediatr Source Type: research

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ConclusionRadioembolization after systemic radionuclide treatments is safe, and the occurrence of radioembolization-induced liver disease is rare.Level of Evidence4, case series.
Source: CardioVascular and Interventional Radiology - Category: Radiology Source Type: research
ConclusionThe results show excellent vessel patency and a good safety profile up to 1  year in the subgroup of Japanese patients in IMPERIAL treated with Eluvia for femoropopliteal artery disease.Level of EvidenceLevel 3; subgroup analysis of randomized trial.Clinical Trial RegistrationClinicalTrials.gov, identifier NCT02574481.
Source: CardioVascular and Interventional Radiology - Category: Radiology Source Type: research
Authors: Selladurai S, Thittai AK Abstract In conventional linear array (CLA)-based elastography tissue compression in one direction (e.g., axial) leads to an expansion in all other directions (lateral, elevation). Therefore, the estimation of the lateral displacements and strains may provide additional information on the tissue mechanical properties. However, these are not exploited fully due to the inherent limitation in lateral sampling. Recently, a method named actuator-assisted beam translation (ABT) was demonstrated to address this issue, wherein the focused beam was translated at subpitch locations using an ...
Source: Ultrasonic Imaging - Category: Radiology Tags: Ultrason Imaging Source Type: research
Authors: Islam MT, Righetti R Abstract Ultrasound poroelastography is a cost-effective and noninvasive imaging technique, which can be used to reconstruct mechanical parameters of tissues such as Young's modulus, Poisson's ratio, interstitial permeability, and vascular permeability. To estimate interstitial permeability and vascular permeability using poroelastography, accurate estimation of the strain time constant (TC) is required. This can be a challenging task due to the nonlinearity of the exponential strain curve and noise affecting the experimental data. Due to motion artifacts caused by the sonographer, ani...
Source: Ultrasonic Imaging - Category: Radiology Tags: Ultrason Imaging Source Type: research
Authors: Lindsey BD, Collins GC Abstract Ultrasonic coda wave analysis techniques localize defects in fields such as seismography and nondestructive testing. In medical ultrasound, these techniques might provide novel mapping of tissue properties in diseases characterized by local fibrosis. In this work, we present an approach for localizing variation in scattering properties in the diffuse regime with an array transducer in medical ultrasound. This approach estimates coda wave decorrelation as the array is displaced by 0.5 mm, allowing data acquisition at two slightly different spatial locations. An inverse proble...
Source: Ultrasonic Imaging - Category: Radiology Tags: Ultrason Imaging Source Type: research
Publication date: Available online 15 January 2020Source: Trends in Cognitive SciencesAuthor(s): Simon Ruch, Katharina HenkeCan information that is processed during sleep influence awake behavior? Recent research demonstrates that learning during sleep is possible, but that sleep-learning invariably produces memory traces that are consciously inaccessible in the awake state. Thus, sleep-learning can likely exert implicit, but not explicit, influences on awake behavior.
Source: Trends in Cognitive Sciences - Category: Psychiatry & Psychology Source Type: research
Publication date: Available online 15 January 2020Source: Aggression and Violent BehaviorAuthor(s): Tobore Onojighofia ToboreAbstractAlcohol use is known to result in disinhibition. However, evidence suggests that alcohol consumption could also result in inhibition. Several hypotheses have been proposed for this confounding alcohol-induced behavior, but none explains it adequately at the level of the brain. In this paper, oxidative stress is put forth as the underlying cause of alcohol toxicity and behavioral impairments. The implications of this understanding and how oxidative stress influences behavior in obesity, diabet...
Source: Aggression and Violent Behavior - Category: Psychiatry & Psychology Source Type: research
The materials here report on efforts to screen for small molecule compounds that can reduce the age-related decline of mitochondrial function observed in neurons - and indeed throughout the body. Screening the contents of compound libraries is a process that might sound simple, and conceptually it is, but it is a complex task to build a cost-effective system and supporting logistics to screen for a novel outcome. In this case the outcome is a reversal of at least some degree of reduced mitochondrial function in neurons from old tissue, as well as improvement in important aspects of neural function. Every cell contai...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
This study was conducted between January 1, 2019, and July 25, 2019, at the neurology and biochemistry clinics of two different tertiary hospitals simultaneously. Overall, 50 RRMS patients with migraine, 50 RRMS patients without migraine, and 50 healthy volunteers were included in the study. The participants’ vitamin D, VITDBP, VITDR, hs-CRP, SOD, CAT, GSH-Px, TAS, TOS, and OSI values were measured.Results: The vitamin D and VITDR values of the RRMS patients with migraine were lower than those of the RRMS patients without migraine (respectively, p = 0.014, p
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 15 January 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Saly H. Elkholy, Shaimaa I. El-Jaafary, Mohamed S. Kotb, Amira M. El Gohary, Bodour A. ElbhyAbstractOptic neuritis (ON) is an inflammatory demyelinating condition that causes acute - usually monocular - visual loss. It is highly associated with multiple sclerosis (MS). In general, ON is a clinical diagnosis based upon the history and examination findings.Objective: The aim was to assess the diagnostic accuracy of measuring optic nerve sheath diameter (ONSD) by ultrasound in acute optic neuritis.Methods: This is a pr...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
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