Growth inhibition of Saos-2 osteosarcoma cells by lactucopicrin is mediated via inhibition of cell migration and invasion, sub-G1 cell cycle disruption, apoptosis induction and Raf signalling pathway.

CONCLUSIONS: Lactucopicrin exhibits significant antiproliferative effects on the osteosarcoma cells and may prove essential in the development of systemic therapy for this malignancy. PMID: 31786886 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research