AI's clinical role in breast screening comes under scrutiny

The fiercely contested race to demonstrate how artificial intelligence (AI)...Read more on AuntMinnie.comRelated Reading: C-MIMI: AI could cut mammography workload in half AI shows promise for reducing mammography workload AI enhances radiologist performance for DBT Deep learning enhances breast cancer risk assessment SBI: AI improves DBT's performance in dense tissueComments: 12/1/2019 2:21:59 PMHospital-Rad If I were a resident I would think twice before choosing breast fellowship. Although a mammographer won't be replaced by AI completely, I predict that the work volume will decrease dramatically. Screenings will be interpreted by AI and the mammographers will do diagnostics, ultrasound and biopsies which decreases the need for breast imagers dramatically.  As a side note, probably it the time to decrease the number of residents in radiology. I personally don't think this AI will replace radiologists completely during our lifetime but it will decrease the demand for radiologists. It is just a matter of time before the software calls all normal scans normal and leaves the abnormal ones (plus the false positive ones) to the radiologists to interpret. In fact, the software doesn't need to have a good specificity. It just needs to have a high sensitivity. It can call "very normal" exams, normal (which are a great percentage of radiology exams) and then leave the rest to the radiologists.      12/1/2019 2:26:46 PMhey Interesti...
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Authors: Laudisio D, Castellucci B, Barrea L, Pugliese G, Savastano S, Colao A, Muscogiuri G Abstract Breast cancer is the second most frequent type of cancer worldwide and the most commonly occurring malignancy in women, and its incidence is increasing in most developed and developing countries. There is growing evidence that lifestyle factors, in particular diet may be associated with higher Breast Cancer risk. Some evidence exists regarding the benefit of Mediterranean Diet on reduced risk of Breast Cancer in premenopausal and postmenopausal women. The protective effect of the Mediterranean Diet against the risk...
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CONCLUSION: The study identified both a high prevalence of xerostomia regardless of the chemotherapy used and the need to create protocols to improve the quality of life of these patients. PMID: 32965427 [PubMed - in process]
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Authors: Piña-Sánchez P, Valdez-Salazar HA, Ruiz-Tachiquín ME Abstract Breast cancer (BC) is the most common type of cancer in women worldwide, and despite advances in treatments, its incidence and mortality are increasing. Therefore, it is necessary to develop new, non-invasive tests that provide more accurate diagnosis and prognosis in a timely manner. A promising approach is measuring the presence of biomarkers to detect tumors at various stages and determine their specific characteristics, thus allowing for more personalized treatment. MicroRNAs (miRNAs) serve a role in gene expression, pri...
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Role of TG2 and TGF-β1 in the pathogenesis of human breast cancer. Oncol Lett. 2020 Nov;20(5):221 Authors: Gao HC, Huang YZ, Liu YQ, Chen Y, Wang ZH, Yin GH Abstract The present study analyzed the role of transforming growth factor-β1 (TGF-β1) and tissue transglutaminase (TG2) in breast cancer, as well as their protein levels in MCF-7 cells treated with cisplatin. In addition, the present study investigated the effects of TG2 and TGF-β1 in MCF-7 cells following TGF-β1 and TG2 inhibition or TGF-β1 induction. The protein levels of TG2 and TGF-β1 in breast cancer tissues...
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Authors: Wu M, Zhao H Abstract Breast cancer (BC) remains the most common cancer in females. Therefore, the present study aimed to identify key genes involved in the carcinogenesis of BC and to explore their prognostic values by integrating bioinformatics tools. The gene expression profiles of 46 ductal carcinoma in situ (DCIS) and three normal breast tissues from the GSE59248 dataset were downloaded. Differentially expressed genes (DEGs) were subsequently identified using the online tool GEO2R and a functional enrichment analysis was performed. In addition, a protein-protein interaction (PPI) network was construct...
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