Genetic Advance in Depressive Disorder.

This article reviews the candidate genes for MDD and BD, genetic variation loci, chromosome structural variation, new technologies, and new methods. PMID: 31784956 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research

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In conclusion, the Prevotella 2 and Ruminococcaceae UCG-002 genera were identified as potential candidates for distinguishing bipolar disorder and major depressive disorder. Further studies with larger sample sizes, longitudinal designs, and control for other various confounders are warranted.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
IntroductionDepressive and manic episodes of bipolar disorder can interact with sleep complaints, followed by a worsened psychiatric condition. The aim of this study was to examine the interaction of sleep disorders with bipolar disorder in youths during depressive and manic episodes.MethodsThe target population was children and adolescents drawn from the Children and Adolescents Affective Disorder Program. Clinical assessment for current psychiatric diagnosis was done by direct clinical interview, Diagnostic Interview for Children and Adolescents (DSM-IV), and best-estimated clinical consensus. We applied sleep questionna...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Mental health issues affect billions of people across every corner of the globe, touching every community and every family, and mounting evidence shows the issue is worsening. To combat the issue, we need to urgently grow our investment in programs that expand access to care, mental health advocates said at a TIME lunch on Wednesday in Davos, Switzerland. “Invest in the system, invest in our rights,” said Elisha London, founder and CEO of United for Global Mental Health. She called for $1 billion in spending on mental health programs worldwide: “It has to happen now.” The event, held during the annu...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized DavosMentalHealth mental health Source Type: news
Condition:   Bipolar Depression Interventions:   Drug: Mydayis Extended-Release Capsule;   Drug: Placebo Sponsors:   Mayo Clinic;   Lindner Center of HOPE Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: This study demonstrates the potential of the Mood Outcomes Program to create a nationwide "learning health system" for mood disorders. This goal will be further realized as the program expands in reach and scope across additional NNDC sites. PMID: 31960777 [PubMed - as supplied by publisher]
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
Comorbidity is the presence of one or more additional conditions co-occurring with a primary condition. In this episode, host schizophrenic Rachel Star Withers with her cohost Gabe Howard will be discussing comorbidity with schizophrenia. Comorbidity is associated with worse health outcomes, more complex clinical management and increased health care costs. Occupational therapist and host of the podcast Occupied, Brock Cook, will be joining us to discuss ways that he works with people with schizophrenia to manage multiple health issues.  Highlights from “Comorbidity with Schizophrenia” Episode [01:28] What ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Antipsychotic Inside Schizophrenia Mental Health and Wellness Psychiatry Psychology Psychotherapy Bipolar disorder and schizophrenia comorbid comorbid psychiatric conditions Comorbidities Comorbidity Diagnosis Of Schizophrenia Livi Source Type: blogs
Authors: Ali Z, Tegin C, El-Mallakh RS Abstract Introduction: Lurasidone has been approved in the United States as a monotherapy and adjunct for acute bipolar I depression, as well as an antipsychotic for patients with schizophrenia.Areas covered: Herein, the authors review the pharmacodynamics and pharmacokinetics of lurasidone as well and the major randomized clinical trials. The authors also provide their expert opinion.Expert opinion: Lurasidone has not been studied in patients with mania or bipolar psychosis. It has been studied, both as a monotherapy and adjunctive treatment to lithium or valproate, in acute ...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Family therapy focused on building communication and problem-solving skills may benefit youth at high risk of bipolar disorder, according to areport inJAMA Psychiatry. Specifically, the study found that youth with mood symptoms and a family history of bipolar disorder who participated in a four-month program with their parents (and, when possible, siblings) had longer periods between symptoms of depression, mania, hypomania, or mixed episodes (mood episodes) than those who participated in a program with less intensive family involvement.Previous studies show that youth at highest risk of progressing to bipolar disorder ear...
Source: Psychiatr News - Category: Psychiatry Tags: bipolar disorder communication David J. Miklowitz depression family therapy family-focused therapy JAMA Psychiatry manic episodes mood episodes mood symptoms problem solving youth Source Type: research
PURPOSE OF REVIEW: Bipolar disorder has the highest rate of suicide of all psychiatric conditions and is approximately 20-30 times that of the general population. The purpose of this review is to discuss findings relevant to bipolar disorder and suicide. R...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
This study aimed to investigate the risk of self-harm following diagnosis of different psychiatric disorders in an Asian population, through a review of inpatient records retrieved from the Hong Kong Clinical Data Analysis and Reporting System (CDARS).MethodsFor this nested case-control study, the inpatient data of people admitted for any reason to Hong Kong public hospitals, between Jan 1, 2000, and Dec 31, 2010, were extracted from CDARS. Cases were people aged 10 years or older who had been admitted to inpatient care with a first-listed record of psychiatric disorder during the study period. The seven psychiatric disord...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
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