Microfluidic Approach for Highly Efficient Viral Transduction.
Microfluidic Approach for Highly Efficient Viral Transduction.
Methods Mol Biol. 2020;2097:55-65
Authors: Tran R, Lam WA
Abstract
Lentiviral vectors enable gene transfer into target cells, but manufacturing is complex, scale-limited, and costly. Here, we describe the use of microfluidic devices for efficient ex vivo gene transfer. Up to four- to fivefold reductions in viral vector usage and two- to fourfold reductions in transduction times can be obtained by using this method.
PMID: 31776918 [PubMed - in process]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tran R, Lam WA Tags: Methods Mol Biol Source Type: research
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