Pathophysiological mechanisms of subvalvular repair and its clinical implications

Publication date: Available online 30 November 2019Source: The Annals of Thoracic SurgeryAuthor(s): Francesco Nappi, Sanjeet Singh Avtaar Singh, Federico Gentile
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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Publication date: Available online 28 January 2020Source: Personality and Individual DifferencesAuthor(s): Gareth Norris, Alexandra BrookesAbstractThe growth in social communication facilitated by technology mean that online scams represent a growing societal issue, with perpetrators successfully persuading people to make fraudulent payments or download malicious attachments. Incidents of online scams have continued to increase across the world, aided by technology that allows fraudsters to mimic communications so as to appear to come from legitimate sources. Much of the previous literature has focused on dispositional fac...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
Although in vitro studies have shown that nicotine influences stem cell proliferation and osteogenesis [1,2], efficacy of smoking cessation is still sparse [3]. Therefore, the aim of this study is to understand the effect of the nicotine cessation period on osteogenic differentiation of bone marrow derived stem cells (BMSCs) which are the key players in bone regeneration and repair.
Source: The Spine Journal - Category: Orthopaedics Authors: Tags: Research Letter Source Type: research
Macrophages are a type of innate immune cell, and like all immune cells are involved in a great many processes in the body, ranging from tissue regeneration to clearing out molecular waste and debris to destruction of pathogens. Macrophages, and the similar microglia of the central nervous system, adopt different phenotypes, known as polarizations, depending on environment and the task at hand. The M1 polarization is pro-inflammatory and focused on ingestion of pathogens and debris, while the M2 polarization is anti-inflammatory and focused on regeneration. These are broad buckets and as such not truly representative of th...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Publication date: Available online 28 January 2020Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Guanning Nina Lu, Shaun C. DesaiThe lips play a principle role in the lower third of the face. Defects of the lips can result in profound functional and aesthetic consequences. Small to medium sized full thickness defects of the lip are amenable to primary closure and can yield excellent results. Partial thickness cutaneous defects may be amenable to local flap techniques or conversion to a full thickness defect for primary closure. By understanding the anatomic basis, patient factors, defect cha...
Source: Operative Techniques in Otolaryngology Head and Neck Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 27 January 2020Source: Pharmacology &TherapeuticsAuthor(s): Erik Laurini, Domenico Marson, Alice Fermeglia, Suzana Aulic, Maurizio Fermeglia, Sabrina PriclAbstractThe maintenance of genome integrity is essential for any organism survival and for the inheritance of traits to offspring. To the purpose, cells have developed a complex DNA repair system to defend the genetic information against both endogenous and exogenous sources of damage. Accordingly, multiple repair pathways can be aroused from the diverse forms of DNA lesions, which can be effective per se or via crosstalk with other...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Conditions:   Spina Bifida;   Fetus Risk;   Myelomeningocele Intervention:   Device: NEOX Cord 1K applied fetoscopically Sponsor:   The University of Texas Health Science Center, Houston Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 28 January 2020Source: Materials LettersAuthor(s): Chunrong Yang, Huazhong Wu, Guanghui LiAbstractThe goal of this study is to construct bone scaffolds with neuroregulatory function. The scaffolds were prepared using bioglass (BG) powder, collagen (COL) solution, phosphatidylserine (PS) and ophiopogonin loaded COL microspheres as the main components. Combinatorial processing techniques involving chemical-crosslinking and freeze-drying were used. The resultant scaffold constructs were characterized in terms of their morphology, drug release kinetics, pharmacological and biological activiti...
Source: Materials Letters - Category: Materials Science Source Type: research
Publication date: Available online 28 January 2020Source: The Annals of Thoracic SurgeryAuthor(s): Sameer Hirji, Farhang Yazdchi, Spencer Kiehm, Samantha Landino, Siobhan McGurk, Jochen Muehlschlegel, Steve Singh, Hari Mallidi, Marc Pelletier, Sary Aranki, Prem Shekar, Tsuyoshi KanekoAbstractBackgroundRing annuloplasty (Ring) and suture bicuspidization annuloplasty (Suture-bicuspidization) are two utilized techniques for tricuspid valve repair. With the emergence of transcatheter tricuspid valve repair technologies that mimic these conventional surgical techniques, we compared their mid-term outcomes and longitudinal echoc...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 27 January 2020Source: The Annals of Thoracic SurgeryAuthor(s): Joseph V. Lombardi, G. Chad Hughes, Jehangir J. Appoo, Joseph E. Bavaria, Adam W. Beck, Richard P. Cambria, Kristofer Charlton-Ouw, Mohammad H. Eslami, Karen M. Kim, Bradley G. Leshnower, Thomas Maldonado, T. Brett Reece, Grace J. WangThis Society for Vascular Surgery/Society of Thoracic Surgeons (SVS/STS) document illustrates and defines the overall nomenclature associated with type B aortic dissection. The contents describe a new classification system for practical use and reporting that includes the aortic arch. Chron...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
CONCLUSION: Upper GI surgeons need to have an index of suspicion for PEDH. They must investigate and operate these patients if this complication develops, since an immediate surgery has a high mortality and poor outcome. PMID: 31983091 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
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