ITRAQ-based quantitative proteomics reveals the first proteome profiles of piglets infected with porcine circovirus type 3.

This study attempted for the first time to investigate the protein profile of PCV3-infected piglets using iTRAQ technology; our findings provide valuable information to better understand the mechanisms underlying the host responses to PCV3 infection in piglets. SIGNIFICANCE: Our study identified differentially abundant proteins related to a variety of potential signaling pathways in the lungs of PCV3-infected piglets. These findings provide valuable information to better understand the mechanisms of host responses to PCV3 infection.
PMID: 31785380 [PubMed - as supplied by publisher]

Source: Journal of Proteomics - November 26, 2019 Category: Biochemistry Authors: Jiang H, Wei L, Wang D, Wang J, Zhu S, She R, Liu T, Tian J, Quan R, Hou L, Li Z, Chu J, Zhou J, Guo Y, Xi Y, Song H, Yuan F, Liu J Tags: J Proteomics Source Type: research