Molecular networking-based dereplication of strictosidine-derived monoterpene indole alkaloids from the curare ingredient Strychnos peckii.

CONCLUSIONS: The use of MN combined with the analysis of the fragmentation patterns showed to be a useful strategy for the dereplication of strictosidine-derived MIAs from S. peckii, highlighting known and unprecedented structures, as well as useful diagnostic product ions. Therefore, this workflow is an effective approach for the characterization of strictosidine-type alkaloids in future dereplication works.
PMID: 31783430 [PubMed - as supplied by publisher]

Source: Rapid Communications in Mass Spectrometry : RCM - November 28, 2019 Category: Chemistry Authors: Santos CLG, Angolini CFF, Neves KOG, Costa EV, de Souza ADL, Pinheiro MLB, Koolen HHF, da Silva FMA Tags: Rapid Commun Mass Spectrom Source Type: research