Epithelial Mesenchymal and Endothelial Mesenchymal Transitions in Hepatocellular Carcinoma: A Review.

Conclusion: The metastatic pathway of HCC seems to be related to the Wnt- or, rather, TGFβ1-mediated inflammation-angiogenesis-EMT-CSCs crosstalk link. Molecular therapy should target this molecular axis controlling the HCC microenvironment.
PMID: 31781608 [PubMed - in process]

Source: Biomed Res - December 1, 2019 Category: Research Authors: Gurzu S, Kobori L, Fodor D, Jung I Tags: Biomed Res Int Source Type: research