Spontaneous lung herniation after forceful coughing

Spontaneous lung herniation is a rare finding, most often the result of forceful coughing. Risk factors include obesity, male gender, tobacco use, and steroid use. Surgical repair is recommended due to increasing size of herniation and pain control. Life style modification, such as smoking cessation, is recommended in this patient population.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research

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CONCLUSIONS: LA repair of PUH is feasible for patients with a raised BMI and does not result in higher postoperative pain scores or the need for higher doses of LA. PMID: 31951146 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - Category: Surgery Authors: Tags: Ann R Coll Surg Engl Source Type: research
This study presents the effects of berberine (BBR) on the aging process resulting in a promising extension of lifespan in model organisms. BBR extended the replicative lifespan, improved the morphology, and boosted rejuvenation markers of replicative senescence in human fetal lung diploid fibroblasts. BBR also rescued senescent cells with late population doubling (PD). Furthermore, the senescence-associated β-galactosidase (SA-β-gal)-positive cell rates of late PD cells grown in the BBR-containing medium were ~72% lower than those of control cells, and its morphology resembled that of young cells. Mechanistically...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ConclusionsTo our best knowledge, this study is the first to present outcomes of morbidly obese patients who underwent RVHR. The results indicate the safety and efficacy of RVHR in morbid obesity with a low recurrence rate as well as a long freedom-of-recurrence time. Further studies are needed to better elucidate the role of robotic surgery in morbidly obese patients.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Post-bariatric, de-novo hiatal hernias are associated with a cluster of symptoms including Bloating (nausea/vomiting), Abdominal pain, Regurgitation, and Food intolerance or dysphagia (BARF). Patients with this cluster are at risk mis-diagnosis, malnutrition and maladaptive eating.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
A 55 y/o Female, current BMI 31 underwent a laparoscopic ante-colic, ante-gastric Roux-en-Y gastric bypass 6 years prior to presentation to our practice. Her original surgery and recovery were unremarkable and she had excellent weight loss. Recently, she has had a 5-month history of progressive dysphagia, regurgitation, reflux, and cough. Additional symptoms include chest pain and occasional vomiting with relief of symptoms. As part of a workup for her symptoms, an UGI demonstrates gastric pouch migration to the mediastinum with a radiographic diagnosis of “achalasia” due to a birds-beak appearance of the gastr...
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
A unique case of intractable hiccups. Patient is 48 years old with severe hiccups followed by burping which relieves his chest pain, nausea and vomiting, and severe heartburn and reflux. He has a remote history of Nissen fundoplication that was revised into a roux en y gastric bypass. He also had a prior hiatal hernia repair. This over time yielded weight loss and resolution of symptoms. The then had the above symptoms start with findings as described by the video presentation.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
Gastrocutaneous fistula after gastric bypass is a rare complication. Causes include iatrogenic, traumatic or inflammatory etiologies. Pain and wound complications are debilitating. Multiple approaches exist including percutaneous, endoscopic, and surgical options. Endoscopic approaches involve clipping and fistula plugs and stenting to seal and exclude the fistula.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
We present the first case of bariatric surgery in a patient with Ehlers-Danlos syndrome and outline management challenges in the context of the relevant literature. A 56-year-old man with type IV Ehlers-Danlos syndrome and a body mass index of 41.8 kg/m2 was referred to the bariatric centre of the Churchill Hospital, Oxford, for consideration of surgery for morbid obesity. His comorbidity included type 2 diabetes, hypertension, dyslipidaemia and obstructive sleep apnoea. He underwent a laparoscopic Roux-en-Y gastric bypass. His initial recovery was uneventful and he was discharged on the first postoperative day. Six weeks ...
Source: Annals of the Royal College of Surgeons of England - Category: Surgery Authors: Tags: Ann R Coll Surg Engl Source Type: research
Conclusions: Between January and December 2018, 33 patients underwent surgery between two units. Indications for surgery included dysfunctional uterine bleeding, endometrial hyperplasia, pelvic pain, post-menopausal bleeding, prophylactic surgery in BRCA positive patients and one grade 1 stage 1 endometrial cancer in whom laparoscopic hysterectomy was technically difficult and complicated by previous midline laparotomy. Ages ranged from 35-75 and BMI from 20-53.Mean operation time was 68.5 minutes and mean blood loss intraoperatively was 269mls. 15.2% (n = 5) had a blood loss equal or more than 500&thi...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
In conclusion, in the absence of obesity, visceral adipose tissue possesses a pronounced anti-inflammatory phenotype during aging which is further enhanced by exercise. Methods of Inducing Cellular Damage are Rarely Relevant to Aging, and the Details Matter https://www.fightaging.org/archives/2019/08/methods-of-inducing-cellular-damage-are-rarely-relevant-to-aging-and-the-details-matter/ One of the major challenges in aging research is determining whether or not models of cellular or organismal damage and its consequences are in any way relevant to the natural processes of aging. One can hit a brick with...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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