Protection of blood-brain barrier as a potential mechanism for enriched environments to improve cognitive impairment caused by chronic cerebral hypoperfusion.
CONCLUSIONS: These results suggest that protection of the BBB may be a novel mechanism by which EEs ameliorate CCH-induced cognitive impairment, and this effect may be related to the activation of the Wnt/β-catenin pathway.
PMID: 31778736 [PubMed - as supplied by publisher]
Source: Behavioural Brain Research - Category: Neurology Authors: Qu C, Xu L, Shen J, Li Y, Qu C, Song H, Zhang J Tags: Behav Brain Res Source Type: research