Quantifying how much attention rodents allocate to motivationally-salient objects with a novel object preference test.

Quantifying how much attention rodents allocate to motivationally-salient objects with a novel object preference test.
Behav Brain Res. 2019 Nov 26;:112389
Authors: Hornoiu I, Gigg J, Talmi D
Abstract
The allocation of attention can be modulated by the emotional value of a stimulus. In order to understand the biasing influence of emotion on attention allocation further, we require an animal test of how motivational salience modulates attention. In mice, female odour triggers arousal and elicits emotional responses in males. Here, we determined the extent to which objects labelled with female odour modulated the attention of C57BL/6 J male mice. Seven experiments were conducted, using a modified version of the spontaneous Novel Object Recognition task. Attention was operationalised as differential exploration time of identical objects that were labelled with either female mouse odour (O+), a non-social odour, almond odour (Oa) or not labelled with any odour (O-). In some experiments we tested trial unique (novel) objects than never carried an odour (X-). Using this novel object preference test we found that when single objects were presented, as well as when two objects were presented simultaneously (so competed with each other for attention), O + received preferential attention compared to O-. This result was independent of whether O + was at a novel or familiar location. When compared with Oa at a novel location, O + a...

Source: Behavioural Brain Research - November 25, 2019 Category: Neurology Authors: Hornoiu I, Gigg J, Talmi D Tags: Behav Brain Res Source Type: research