Intraluminal thrombus in abdominal aortic aneurysm: a friend or a foe?
Intraluminal thrombus in abdominal aortic aneurysm: a friend or a foe? Int Angiol. 2019 Nov 25;: Authors: Simka M, Hobot J, Skuła M PMID: 31782282 [PubMed - as supplied by publisher]
We were pleased to read the interesting paper by Mufty et al. regarding their mid- and long-term results of the Ovation stent-graft system applied in 74 patients with Abdominal Aortic Aneurysms (AAA).1 Among their findings, the Authors report a relatively lower incidence of initial technical success (91.9%), attributing this to the high percentage of challenging AAA necks.1 The Authors report an 83.8% of hostile necks with respect to neck calcification (59%), circular or semicircular thrombus (12% and 27%, respectively), reverse-tapered neck morphology (24%) and combination of at least 2 factors in some cases.
Τηε afx unibody bifurcated unibody aortic endograft for the treatment of Abdominal Aortic aneurysms: current evidence and future perspectives. Expert Rev Med Devices. 2019 Dec 13;: Authors: Georgakarakos E, Ioannidis G, Koutsoumpelis A, Papatheodorou N, Argyriou C, Spanos K, Giannoukas AD, Georgiadis GS Abstract Introduction: AFX is a bifurcated unibody aortic endograft for the treatment of Abdominal Aortic aneurysms. It consists of an inner metallic endoskeleton with multiple metallic struts covered by a polytetrafluoroethylene graft fabric. The endoskeleton is sutured to the outer fab...
Abstract In this paper, we study the correlation between the wall shear stress, a hemodynamical index derived from numerical simulations, and an new index MFA-ILT for the characterization of intraluminal thrombus (ILT) in the presence of abdominal aortic aneurysms. Based on the processing of medical images, we define our index MFA-ILT by projecting onto lumen surface a measure of the ILT thickness. From the physical point of view, hemodynamical indexes describe the mechanical stimuli at which the luminal surface of the vessel wall is subject to, due to blood flow. Specifically, we consider the time-averaged wall s...
Introduction: Macrophages in the aneurysmal wall play an important role in the pathogenesis of abdominal aortic aneurysms (AAAs). superparamagnetic iron oxide (SPIO) is a macrophage-specific contrast agent that result in negative enhancement on T2*-weighted imaging. SPIO-enhanced MRI targeting the mural thrombus of AAAs was reported, and the signal level of thrombi showed a decrease after SPIO injection. However, the macrophages in the media and adventitia of AAA wall has not been investigated in detail.
Introduction - Shaggy aorta is related to early adverse events following endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm, specially peripheral and visceral embolization from the aorta.
Introduction - The intra-luminal thrombus (ILT) in abdominal aortic aneurysms (AAA) is suggested to weaken the aortic wall and contribute to aneurysm growth and eventually rupture (1 –4). Thus, investigation of ILT has the potential to improve rupture risk prediction which today is predominantly based on diameter alone. Until recently, the ILT volume could only be determined by means of three-dimensional computed tomography angiography (3D-CTA) and ultrasound has not had a pla ce in this context, although attractive due to its noninvasive nature.
Introduction - Most clinically relevant abdominal aortic aneurysms (AAA) contain an intraluminal thrombus (ILT) 1. The ILT entraps neutrophils, which secrete elastase with fibrinolytic activity, the process of which yields specific ‘neutrophil elastase-derived cross-linked fibrin degradation products’ (E-XDP) 2. Our hypothesis was that circulating E-XDP could reveal the presence, size and mechanical stress of AAAs and its ILTs.
Thrombosis of an endovascular aortic repair (EVAR) is a devastating complication of a common surgical procedure that can lead to serious morbidity and mortality if not promptly recognized. This is the first case report of an EVAR graft thrombosis in the emergency medicine literature.
Intraluminal thrombus (ILT) is almost ubiquitously associated with abdominal aortic aneurysm (AAA), but its role in the pathophysiologic mechanism of AAA remains unclear after more than two decades of speculation. This systematic review and meta-analysis reached the not surprising conclusion that larger AAAs have more ILT than small AAAs. It, however, still stops short of concluding whether ILT is a contributing or protective factor for aneurysm rupture.1
This study investigated the interrelation between plasma D-dimer level, ILT volume, AAA size and progression.Main methodsThis was a retrospective observational study that involved 181 patients with infra-renal AAA. They were divided into small and large AAA groups according to AAA diameter. 24 of them had repeated abdominal computed tomography angiography (CTA) scan and were divided into slow-growing and fast-growing AAA groups according to the median value of AAA growth rate. Baseline and follow-up plasma D-dimer level, maximum diameter of AAA, total infra-renal aortic volume and ILT volume were analyzed.Key findingsPlasm...