Immunomodulating action of the 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3 ′,4′-methylenedioxyphenyl]-coumarin in neutrophils from patients with rheumatoid arthritis and in rats with acute joint inflammation

ConclusionAltogether, the results reported herein indicate that 3-PD-5 is a promising modulator of the early stages of acute joint inflammation that can help to diminish not only excessive neutrophil infiltration in the synovia but also neutrophil activation and its outcomes in RA patients.
Source: Inflammation Research - Category: Research Source Type: research