High Intensity Focused Ultrasound (HIFU) for the treatment of varicose veins and venous leg ulcers - a new non-invasive procedure and a potentially disruptive technology.

High Intensity Focused Ultrasound (HIFU) for the treatment of varicose veins and venous leg ulcers - a new non-invasive procedure and a potentially disruptive technology. Curr Med Res Opin. 2019 Nov 28;:1 Authors: Whiteley MS PMID: 31775537 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research

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This study evaluates the clinical and patient reported outcomes with and without post-procedure leg compression following radiofrequency ablation (RFA).
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Randomised Clinical Trial Source Type: research
Abstract Background Chronic Venous Disease (CVD) is the main cause of chronic leg ulcers. Varicose veins are the most frequent cause of venous leg ulcers (VLU). 50.9% of Brazilian women have varicose veins and ulcer prevalence is as high as 4%. Ultrasound-guided foam sclerotherapy (UGFS) is a low-cost treatment option for varicose veins. Objectives To analyze UGFS outcomes in patients with VLU. Methods Prospective consecutive single center cohort study. Patients with great saphenous vein (GSV) reflux and VLU were treated and followed-up for 180 days. The following were studied: quality of life (QoL), disease severity, heal...
Source: Jornal Vascular Brasileiro - Category: Surgery Source Type: research
Authors: Nishibe T, Nishibe M, Akiyama S, Nukaga S, Ogino H, Koizumi J, Dardik A Abstract BACKGROUND: To quantitatively evaluate edema of the lower legs in patients with saphenous varicose veins, and to determine the association between leg edema and venous hemodynamics of the lower legs. METHODS: The data of 140 patients with saphenous varicose veins visiting Eniwa Midorino Clinic from April 2018 to November 2019 were retrospectively analyzed. Body composition values, including mass index (BMI), extracellular water / total body water (ECW/TBW) of each leg, and skeletal muscle mass of each leg, were measured by...
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
Authors: Yetkin E, Ozturk S, Cuglan B, Turhan H Abstract Lower extremity venous diseases or insufficiency include clinically deteriorating conditions with morphological and functional alterations of the venous system including venous hypertension, vascular wall structural abnormality, and venous valvar incompetency in association with a inflammatory process . In fact the same pathophysiological processes are the main underlying mechanisms of other venous insufficiencies in different vascular territories such as varicocele, pelvic varicosities or congestion syndrome and hemorrhoids.Regarding the anatomical continuit...
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
Recently published paper authored by Chait et al1 drew our attention as being a large retrospective, single-center study (>10,000 procedures) looking into the occurrence of endovenous heat-induced thrombosis (EHIT) after radiofrequency (RFA) and endovenous laser ablation (EVLA) for varicose veins. The authors concluded that RFA poses a significantly higher risk of EHIT when compared to EVLA. However, reading the paper disclosed numerous flaws and misinterpretations. In fact Table II showed that there was definitely no any increase in EHIT incidence after the RFA procedures but it was actually lower.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Source Type: research
Conclusion: These results support strongly the effectiveness and safety of HIFU for ablating non-invasively veins. PMID: 32133898 [PubMed - in process]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Authors: Hartmann K Abstract Thermal ablation of saphenous vein varicosis has developed into a standard procedure for treatment of varicose veins. The clinical success of the endovenous thermal procedure is comparable to high ligation and stripping operations and a significant difference between these groups could not be detected in long-term analyses. The only difference is in the genesis of saphenofemoral recurrence detected by duplex ultrasound: neoangiogenesis occurs after high ligation and stripping operation and after endovenous ablation of the great saphenous vein a recurrence occurs predominantly via a resi...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Abstract: High pressure in the lower-limb veins is often associated with chronic venous insufficiency and varicose veins (VVs), making it important to search for the mechanisms and agents that control venous function. We have shown that protracted increases in venous stretch/wall tension reduce vein contraction and augment matrix metalloproteinase (MMP)-2 and -9. Also, MMP-2 and MMP-9 promote venodilation, a hallmark of VVs. Sulodexide (SDX) is a blend of glycosaminoglycans with efficient profibrinolysis and antithrombosis activities, but its actions on vein function and the mechanisms involved are unclear. We tested the...
Source: Journal of Cardiovascular Pharmacology - Category: Cardiology Tags: Original Article Source Type: research
In conclusion, the application of TS combined with NPWT in THLS can not only alleviate subcutaneous ecchymosis and pain, but also prevent the occurrence of subcutaneous ecchymosis and pain after operation. Therefore, it is conducive to postoperative recovery and is suitable for clinical application.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Quality Improvement Study Source Type: research
AbstractA 76-year-old woman was attacked by a domestic rooster on her rural property while collecting eggs. The bird pecked her lower left leg causing significant hemorrhage with collapse and death. The decedent ’s past medical history included treated hypertension, hyperlipidemia, non-insulin dependent diabetes mellitus and varicose veins. At autopsy the major findings were limited to the lower left leg which was covered with adherent dried blood. Two small bleeding lacerations were present, one of which was located immediately over a perforated large varix. Death was therefore due to exsanguination from bleeding va...
Source: Forensic Science, Medicine, and Pathology - Category: Forensic Medicine Source Type: research
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