The best outcomes for going through pregnancy with diabetes —Clinical features of four recipients of the Lilly Insulin 50-Year Award—

This report focuses on the clinical features of these recipients with succ essful delivery of newborns at Tokyo Women’s Medical University approximately 40–50 years ago. Three of the recipients [type 2 diabetes,n  =  2 (cases 1 and 3); type 1 diabetes,n  =  1 (case 4)] were treated before, during and after pregnancy, whereas one patient with type 2 diabetes (case 2) was only treated during pregnancy. Even though three recipients had a past history of stillbirth due to insufficient control of diabetes, all four recipients were directed to try to main tain normoglycemia before and during pregnancy, which resulted in the delivery of newborns without major events. The current ages of the recipients are 82, 78, 78 and 63 years old, respectively. No diabetic complications were observed in case 1. However, simple retinopathy occurred after ophthalmol ogical treatment in case 3, and case 2 has received hemodialysis. Nevertheless, all of the patients have spent active lives with the confidence of successful delivery, even though none of the patient's HbA1c levels fell below 7% after delivery. The authors as their doctors are proud of the continuou s efforts made by these four recipients to receive diabetes treatment before, during and after pregnancy. We therefore advocate “the best outcome for going through pregnancy with diabetes” to all diabetic patients who hope to become pregnant based on a planned pregnancy with the n...
Source: Diabetology International - Category: Endocrinology Source Type: research

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Authors: K V, Rm S Abstract Aims and Objectives: To evaluate the adequacy of glycaemic, lipid and blood pressure (BP) goals of diabetic patients, To evaluate the differences in goal attainment rates between various parameters like age, sex, body mass index, complications, medications and compliance. Materials and Methods: A total of 250 diabetic patients coming to HIMS, Hassan were studied and evaluated for BP, fasting blood sugar (FBS) , post prandial blood sugar (PPBS), glycosylated haemoglobin (HbA1c), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides (TG). Patients were evaluat...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
CONCLUSIONS: Breakfast consumption
Source: The American Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Am J Clin Nutr Source Type: research
ConclusionIncreased expression levels of KISS1 and KISS1R in case of diabetes mellitus may play a role in the altered placentation process and lead to the development of preeclampsia.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Abstract OBJECTIVE: To estimate whether women with diabetes are at risk for 60-day postpartum readmissions and associated complications. METHODS: The Nationwide Readmissions Database from 2010 to 2014 was analyzed to determine risk for 60-day postpartum readmissions among women with type 1 diabetes mellitus (DM), type 2 DM, gestational diabetes mellitus (GDM), and unspecified DM compared with women with no diabetes. Secondary outcomes included evaluating risk for overall severe maternal morbidity during readmissions, as well as wound complications, acute diabetic complications such as diabetic ketoacidosis, v...
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
Publication date: December 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 8Author(s): Lisa D. Alexander, George Tomlinson, Denice S. FeigAbstractObjectiveOur aim in this study was to compare the effects of risk factors for large-for-gestational-age (LGA) birthweight between women with type 1 and type 2 diabetes mellitus (TIDM and T2DM, respectively).MethodsA retrospective cohort study was conducted for women with T1DM (n=152) and T2DM (n=255) attending a diabetes/pregnancy clinic during the period from 2009 to 2016. Multiple logistic regression analysis was used to identify variables associated with LGA birthwe...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
CONCLUSION: Pregnancy provides an important opportunity for health professionals to educate and support women with pre-pregnancy diabetes about their breastfeeding intentions. PMID: 31239238 [PubMed - as supplied by publisher]
Source: Women Birth - Category: Midwifery Authors: Tags: Women Birth Source Type: research
Breastfeeding has significant health benefits for maternal and infant health, yet women with pre-pregnancy diabetes (type 1 or type 2 diabetes mellitus) are often less likely to breastfeed compared with other childbearing women.
Source: Women and Birth - Category: Midwifery Authors: Source Type: research
CONCLUSIONS: Two new studies (406 women) have been incorporated to one of the comparisons for this update. Although the evidence suggests that CGM in comparison to intermittent glucose monitoring may reduce hypertensive disorders of pregnancy, this did not translate into a clear reduction for pre-eclampsia, and so this result should be viewed with caution. No differences were observed for other primary outcomes for this comparison. The evidence base for the effectiveness of other monitoring techniques analysed in the other five comparisons is weak and based on mainly single studies with very low-quality evidence. Additiona...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Sarah K. Azzam1, Wael M. Osman2, Sungmun Lee1, Kinda Khalaf1, Ahsan H. Khandoker1, Wael Almahmeed3,4, Herbert F. Jelinek5 and Habiba S. Al Safar1,2* 1Biomedical Engineering Department, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates 2Khalifa University Center of Biotechnology, Abu Dhabi, United Arab Emirates 3Institute of Cardiac Science, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates 4Heart and Vascular Institute, Cleveland Clinic, Abu Dhabi, United Arab Emirates 5Australian School of Advanced Medicine, Sydney and School of Community Health, Charles Sturt University, Ma...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
CONCLUSION: Studying proteome changes in diabetes can deepen our understanding of the biomolecular basis of disease and help us acquire more efficient therapies. PMID: 31038056 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
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