Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator-driven, open-label, randomized, noninferiority controlled trial

Colistin is recommended in the empirical treatment of ventilator-associated pneumonia (VAP) with a high prevalence of carbapenem-resistant gram-negative bacilli (CR-GNB). However, the efficacy and safety of co...
Source: Critical Care - Category: Intensive Care Authors: Tags: Research Source Type: research

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Forty - one patients ID'd with virus as of Jan. 2, 2020; all had pneumonia with abnormal chest CT findings
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Gynecology, Infections, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Pathology, Pulmonology, Journal, Source Type: news
Conditions:   Child, Hospitalized;   Vitamin D Deficiency;   Pneumonia Intervention:   Drug: A single one ml injection Sponsor:   Cairo University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
As researchers fight to stop the spread of a novel coronavirus that originated in a seafood market in the central Chinese city of Wuhan, they are facing a counter-intuitive problem: the symptoms can sometimes be so mild in patients that the virus is very difficult to detect. The Wuhan coronavirus, dubbed 2019-nCoV, has killed at least 106 people in mainland China, out of the 4,400-plus documented cases. According to records released by Chinese health authorities, most fatalities were older or had additional health problems. Severe acute respiratory syndrome (SARS), which is related to 2019-nCoV and killed nearly 800 people...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China Infectious Disease onetime overnight Source Type: news
TUESDAY, Jan. 28, 2020 -- As of Jan. 2, 2020, 41 patients were admitted with laboratory-confirmed 2019 novel coronavirus (2019-nCoV), all of whom had pneumonia, according to a study published online Jan. 24 in The Lancet. Chaolin Huang, M.D., from...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Influenza A virus (IAV) is among the most common causes of pneumonia-related death worldwide. Pulmonary epithelial cells are the primary target for viral infection and replication and respond by releasing inflammatory mediators that recruit immune cells to mount the host response. Severe lung injury and death during IAV infection result from an exuberant host inflammatory response. The linear ubiquitin assembly complex (LUBAC), composed of SHARPIN, HOIL-1L, and HOIP, is a critical regulator of NF-κB–dependent inflammation. Using mice with lung epithelial–specific deletions of HOIL-1L or HOIP in a model of...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Are asthma patients who use inhaled corticosteroids at an increased risk for pneumonia and hospitalization?BMC Pulmonary Medicine
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news
[Nation] Kenyan students in China's Wuhan city have expressed displeasure with how the government is responding to their pleas for help amidst the ongoing global outbreak of a pneumonia-like 2019-nCoV virus.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
“Chinese health authorities say an outbreak of a pneumonia-like illness has sickened 305 people and killed five”…  No, this is not an excerpt from a recent news report about the Wuhan virus, but it is actually one from a CNN piece from 2003 when the SARS outbreak was raging. There are many similarities between the current outbreak to the SARS one from its geolocation to its spread to the viruses themselves.  However, much has changed within the 17 year gap between those two pandemics. For one, technology in the healthcare sector has known an exponential boom. New technologies that were nonex...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence Future of Medicine digital health digital technology epidemics global health coronavirus Source Type: blogs
(Boston University School of Medicine) Researchers have determined that after lungs recover from infection, alveolar macrophages (immune cells that live in the lungs and help protect the lungs against infection) are different in multiple ways and those differences persist indefinitely.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
BOSTON (CBS) – Two people in New Hampshire are undergoing testing for novel coronavirus. Health officials say the two people recently traveled to Wuhan City, China and developed respiratory symptoms. “These people have more mild illness, but both sought healthcare for their illnesses and are recovering,” the New Hampshire Department of Health and Human Services said. “They remain isolated until test results are available.” On Thursday, a student from White Mountain School in Bethlehem went to the emergency room at Littleton Regional Healthcare with mild flu-like symptoms. The student had trave...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Syndicated Local Coronavirus New Hampshire Source Type: news
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